82260-55-7

Upstream product

• 82260-54-6 (3R,4S)-(+)-1-(4-benzyloxy-3-methoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester 
• 56246-53-8 (+)-ethyl cincholoiponate 
• 118-10-5 Cinchonin 
• 1835-12-7 3-methoxy-4-benzyloxy-α-bromoacetophenone 

Downstream Products

• 82310-52-9 (4S,5R)-(-)-5-ethyl-1-(4-hydroxy-3-methoxyphenethyl)-2-oxo-4-piperidineacetic acid ethyl ester 
• 82260-59-1 (4S,5R)-(-)-5-ethyl-1-(4-hydroxy-3-methoxyphenethyl)-2-oxo-4-piperidineacetic acid 
• 98325-30-5 {(S)-1-[2-Acetoxy-2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-3-ethyl-2-oxo-piperidin-4-yl}-acetic acid ethyl ester 
• 98325-31-6 {(4S,5R)-1-[2-Acetoxy-2-(4-benzyloxy-3-methoxy-phenyl)-ethyl]-5-ethyl-2-oxo-piperidin-4-yl}-acetic acid ethyl ester 
• 73053-70-0 (4S,5R)-1-<2-(4-benzyloxy-3-methoxyphenyl)-2-hydroxyethyl>-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 82260-53-5 2-piperidone 

Relevant academic research and scientific papers

Quinolizidines. XII. Synthetic Incorporation of Ethyl Cincholoiponate into a Tricyclic Intermediate Adaptable to Chiral Syntheses of the 10-Hydroxy-9-methoxybenzoquinolizidine-Type Alangium Alkaloids

For the purpose of securing a key intermediate for chiral syntheses of the 10-hydroxy-9-methoxybenzoquinolizidine-type Alangium alkaloids (type 4), the tricyclic ester (-)-15 has been synthesized from ethyl cincholoiponate and 4-benzyloxy-3-met

CONVERSION OF ETHYL CINCHOLOIPONATE INTO A TRICYCLIC INTERMEDIATE ADAPTABLE TO CHIRAL SYNTHESES OF 10-DEMETHYLATED ALANGIUM ALKALOIDS

The title (-)-tricyclic amino ester VII has been synthesized by means of an initial condensation of 4-benzyloxy-3-methoxyphenacyl bromide with (+)-ethyl cincholoiponate (VIII), derived from the Cinchona alkaloid cinchonine, and succeeding steps proceeding