82298-69-9Relevant academic research and scientific papers
Synthesis and biological testing of Acyl-CoA-ketoprofen conjugates as selective irreversible inhibitors of COX-2
Levoin, Nicolas,Chrétien, Fran?oise,Lapicque, Fran?oise,Chapleur, Yves
, p. 753 - 757 (2002)
Ketoprofenoyl-CoA thioester 3 was synthesized by coupling ketoprofen to coenzyme A using the mixed anhydride method. Diastereoisomeric compounds 3a and 3b corresponding to the enantiomers of ketoprofen, were obtained in optically pure form by preparative
