82300-41-2

Upstream product

• 82300-40-1 methyl 3-O-benzyl-4-O-tosyl-6-O-trityl-2-deoxy-α-D-ribo-hexopyranoside 
• 63592-79-0 methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-ribo-hexopyranoside 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 6752-48-3 methyl 2-deoxy-4,6-O-benzylidene-α-D-ribo-hexopyranoside 
• 90761-25-4 methyl 3-O-benzyl-4,6-O-benzylideno-2-deoxy-α-D-ribo-hexoside 
• 98-59-9 p-toluenesulfonyl chloride 
• 82300-39-8 methyl 3-O-benzyl-6-O-trityl-2-deoxy-α-D-ribo-hexopyranoside 
• 64951-98-0 methyl 3-O-benzyl-2-deoxy-α-D-ribo-hexopyranoside 

Downstream Products

• 82300-44-5 methyl 3-O-benzyl-2,4,6-trideoxy-6-iodo-α-D-erythro-hexopyranoside 
• 90691-43-3 (2S,4R,6S)-(E)-6-<2-(4'-fluoro-3,3',5-trimethyl<1,1'-biphenyl>-2-yl)ethenyl>-4-(benzyloxy)-2-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 82300-43-4 methyl 3-O-benzyl-6-O-tosyl-2,4-dideoxy-α-D-erythro-hexopyranoside 
• 90691-42-2 (2S,4R,6S)-1-(4'-fluoro-3,3',5-trimethyl<1,1'-biphenyl>-2-yl)-2-<4-(benzyloxy)-2-methoxy-3,4,5,6-tetrahydro-2H-pyran-6-yl>ethyl phenyl sulfoxide 
• 100295-49-6 (2R,4R,6S)-(E)-6-<2-(4'-fluoro,3,3',5-trimethyl<1,1'-biphenyl>-2-yl)ethenyl>-4-(benzyloxy)-2-methoxy-3,4,5,6-tetrahydro-2H-pyran 
• 82300-45-6 (2S,4R,6S)-2-[2-Benzenesulfonyl-2-(2,4-dichloro-phenyl)-ethyl]-4-benzyloxy-6-methoxy-tetrahydro-pyran 
• 82300-46-7 (2S,4R,6S)-2-[2-Benzenesulfinyl-2-(2,4-dichloro-phenyl)-ethyl]-4-benzyloxy-6-methoxy-tetrahydro-pyran 
• 82300-47-8 (2S,4R,6S)-2-(2-Benzenesulfonyl-2-cyclohexyl-ethyl)-4-benzyloxy-6-methoxy-tetrahydro-pyran 
• 82300-42-3 methyl 3-O-benzyl-2,4-dideoxy-α-D-erythro-hexopyranoside 

Relevant academic research and scientific papers

Synthesis and Utilization of the Chiral Synthon Methyl 3-O-Benzyl-2,4,6-trideoxy-6-iodo-α-D-erythro-hexopyranoside in the Synthesis of a Potent HMG-CoA Reductase Inhibitor

Synthesis of the potent HMG-CoA reductase inhibitor 1a has been achieved by utilizing the chiral synthon 2, which was prepared from methyl α-D-glucopyranoside in 12 steps (6 new).A key step in this sequence, which should have general applicability for the

PROCESS FOR PREPARING INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE VIA A CHIRAL SYNTHON

Totally synthetic analogs of the known inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase, compactin and mevinolin, are prepared from a chiral synthon derived from D-glucose which has the same chirality as the natural products.