82305-05-3

Upstream product

• 638-10-8 ethyl 3-methylbut-2-enoate 
• 1761-63-3 2-hydroxy-5-phenylbenzaldehyde 
• 127952-77-6 4-(2-methylbut-3-yn-2-yloxy)biphenyl 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 92-69-3 4-Phenylphenol 

Downstream Products

• 129621-80-3 (3R,4S)-3-Bromo-2,2-dimethyl-6-phenyl-chroman-4-ol 
• 1215023-91-8 (1aS,7bS)-2,2-dimethyl-6-phenyl-2,7b-dihydro-1aH-oxireno[2,3-c]chromene 
• 129621-72-3 1-((3S,4R)-3-Hydroxy-2,2-dimethyl-6-phenyl-chroman-4-yl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Asymmetric epoxidation of alkenes catalyzed by a porphyrin-inspired manganese complex

A novel strategy for catalytic asymmetric epoxidation of a wide variety of olefins by a porphyrin-inspired chiral manganese complex using H 2O2 as a terminal oxidant in excellent yield with up to greater than 99% ee has been successfully developed.

Asymmetric counteranion-directed transition-metal catalysis: Enantioselective epoxidation of alkenes with Manganese(III) salen phosphate complexes

(Figure Presented) Figure Presentation Paired up: A highly active and enantioselective ion-pair epoxidation catalyst, consisting of an achiral Mn |||-salen complex and a chiral phosphate counteranion, mediates the epoxidization of a wide range of alkenes with high yields and enantioselectivities (see scheme). The unique role of the counteranion is to stabilize an enantiomorphic conformation of the cationic Mn catalyst.

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues

We recently reported that 3,3-dimethyl-3H-benzofuro[3,2,f][1]-benzopyran and its hydrogenated analogue are selective in vitro inhibitors of mycobacterial growth. However, their lack of in vivo activity on a murine model of Mycobacterium tuberculosis infec

Variation in the aromatic ring of cromakalim: Antihypertensive activity of pyranopyridines and 6-alkyl-2H-1-benzopyrans

The synthesis and antihypertensive activity in the spontaneously hypertensive rat of two new series of analogues related to cromakalim (1) are described. In the first series, where the benzopyran nucleus has been replaced by a pyranopyridine nucleus, the

A New Preparative Method of 2,2-Dimethyl-2H-chromenes

2,2-Dimethyl-2H-chromene was prepared from salicylaldehyde and ethyl 3-methyl-2-butenoate (or ethyl α-bromoisobutyrate) in one step.This new method of preparing 2,2-dimethyl-2H-chromene was studied and applied to some 2,2-dimethyl-2H-chromene derivatives.