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5-Bromo-2-chloro-4-(trifluoromethyl)pyridine is a pyridine derivative with the molecular formula C6H3BrClF3N. It features a pyridine ring with a bromine atom at the second position, a chlorine atom at the fourth position, and a trifluoromethyl group also attached to the fourth position. This chemical compound is known for its unique structure and properties, making it a valuable building block in the synthesis of biologically active compounds.

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  • 823221-93-8 Structure
  • Basic information

    1. Product Name: 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE
    2. Synonyms: 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE;Pyridine, 5-broMo-2-chloro-4-(trifluoroMethyl)-
    3. CAS NO:823221-93-8
    4. Molecular Formula: C6H2BrClF3N
    5. Molecular Weight: 260.4389896
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 823221-93-8.mol
  • Chemical Properties

    1. Melting Point: 11-13 °C
    2. Boiling Point: 212.7 °C at 760 mmHg
    3. Flash Point: 82.4 °C
    4. Appearance: /
    5. Density: 1.804 g/cm3
    6. Vapor Pressure: 0.249mmHg at 25°C
    7. Refractive Index: 1.492
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: N/A
    10. PKA: -3.73±0.10(Predicted)
    11. CAS DataBase Reference: 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE(823221-93-8)
    13. EPA Substance Registry System: 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE(823221-93-8)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 823221-93-8(Hazardous Substances Data)

823221-93-8 Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-2-chloro-4-(trifluoromethyl)pyridine is used as a building block for the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new drugs with potential therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Bromo-2-chloro-4-(trifluoromethyl)pyridine serves as a building block for the synthesis of agricultural pesticides. Its properties contribute to the creation of effective pest control agents.
Used as a Reagent in Organic Synthesis:
5-Bromo-2-chloro-4-(trifluoromethyl)pyridine is utilized as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the production of a wide range of organic compounds.
Used as an Intermediate in Specialty Chemicals Manufacturing:
5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE also serves as an intermediate in the manufacturing process of specialty chemicals, where its unique properties are leveraged to produce high-value chemical products.
Used in Medicinal Chemistry:
5-Bromo-2-chloro-4-(trifluoromethyl)pyridine has potential applications in medicinal chemistry, where its structure and properties can be exploited to design and develop new pharmaceutical agents with specific therapeutic targets.
Used in Materials Science:
In the field of materials science, 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE may find use in the development of new materials with unique properties, owing to its distinct structural features and chemical reactivity.
Used in Chemical Research:
5-Bromo-2-chloro-4-(trifluoromethyl)pyridine is also utilized in chemical research, where it can be studied to understand its properties, reactivity, and potential applications in various chemical processes and reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 823221-93-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,3,2,2 and 1 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 823221-93:
(8*8)+(7*2)+(6*3)+(5*2)+(4*2)+(3*1)+(2*9)+(1*3)=138
138 % 10 = 8
So 823221-93-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H2BrClF3N/c7-4-2-12-5(8)1-3(4)6(9,10)11/h1-2H

823221-93-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-BROMO-2-CHLORO-4-(TRIFLUOROMETHYL)PYRIDINE

1.2 Other means of identification

Product number -
Other names QC-7728

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:823221-93-8 SDS

823221-93-8Relevant articles and documents

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

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Paragraph 00162, (2019/04/10)

The present application is directed to compounds of Formula I: (I) compositions comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

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Paragraph 00355, (2017/09/15)

The present application is directed to compounds of Formula I: compounds comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

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Paragraph 00320; 00322-00323, (2017/09/15)

The present application is directed to compounds of Formula I: (I) compositions comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

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