401892-47-5

Basic information

• Product Name: 5-Bromo-2-chloro-4-iodopyridine
• Synonyms: 5-bromo-4-iodo-2-chloropyridine
• CAS NO: 401892-47-5
• Molecular Formula: C₅H₂BrClIN
• Molecular Weight: 318.34
• Mol File: 401892-47-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 149-150°
• Boiling Point: 294.865°C at 760 mmHg
• Flash Point: 132.13°C
• Appearance: /
• Density: 2.396g/cm³
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.674
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2.42±0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-2-chloro-4-iodopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-chloro-4-iodopyridine(401892-47-5)
• EPA Substance Registry System: 5-Bromo-2-chloro-4-iodopyridine(401892-47-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 401892-47-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-chloro-4-iodopyridine is a chemical compound with the molecular formula C5H2BrClIN. It is a pyridine derivative that is commonly used in organic synthesis, particularly in the pharmaceutical industry. 5-Bromo-2-chloro-4-iodopyridine is known for its versatile reactivity and is frequently utilized as a building block in the synthesis of various biologically active molecules. Its unique combination of bromine, chlorine, and iodine substituents make it a valuable intermediate in the production of pharmaceuticals and agrochemicals. Additionally, 5-Bromo-2-chloro-4-iodopyridine is also used as a reagent in the development of new compounds for research and development purposes.

InChI:InChI=1/C5H2BrClIN/c6-3-2-9-5(7)1-4(3)8/h1-2H

Upstream product

• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 401892-48-6 5-bromo-2-chloro-4-(2-chloro-phenyl)-pyridine 
• 1257846-83-5 5-bromo-2-chloro-4-phenylpyridine 
• 1184931-46-1 2-[5-cyclopropyl-2-(2-methoxy-4-morpholin-4-yl-phenylamino)-pyridin-4-ylamino]-N-methyl-benzamide 
• 1184931-47-2 2-[2-(2-methoxy-4-morpholin-4-yl-phenylamino)-5-vinyl-pyridin-4-ylamino]-N-methyl-benzamide 
• 1184931-59-6 2-(2-chloro-5-cyclopropyl-pyridin-4-ylamino)-N-methyl-benzamide 

Relevant articles and documents

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

The present application is directed to compounds of Formula I: (I) compositions comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING

The present application is directed to compounds of Formula I: compounds comprising these compounds and their uses, for example as medicaments for the treatment of diseases, disorders or conditions mediated or treatable by inhibition of binding between WDR5 protein and its binding partners.

2-AMINO SUBSTITUTED PYRIDINE DERIVATIVE

PROBLEM TO BE SOLVED: To provide a 2-amino substituted pyridine derivative useful as an active ingredient of medicines such as antipsychotic agent, anti-anxiety agent, or brain function improver. SOLUTION: The present invention provides a compound represe