82360-26-7

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-oxopiperidin-1-yl)butanoic acid is used as a synthetic intermediate for the development of drugs with potential anti-inflammatory and analgesic properties. Its unique molecular structure and properties make it a valuable tool in drug discovery and development processes.
Used in Medicinal Chemistry Research:
4-(2-oxopiperidin-1-yl)butanoic acid is used as a building block in organic synthesis for the creation of new compounds with potential therapeutic applications. Its structural features and unique properties make it a valuable asset in medicinal chemistry research.
Used in Biochemistry Research:
4-(2-oxopiperidin-1-yl)butanoic acid may have potential applications in biochemistry research, where its unique molecular structure and properties can be utilized to study various biological processes and interactions.

InChI:InChI=1/C9H15NO3/c11-8-4-1-2-6-10(8)7-3-5-9(12)13/h1-7H2,(H,12,13)

Upstream product

• 96-48-0 4-butanolide 
• 675-20-7 piperidin-2-one 
• 1628-89-3 2-methoxypyridine 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 82360-23-4 ethyl 4-(2-oxopyridin-1(2H)-yl)butanoate 
• 154656-90-3 N-(4-(tetrahydropyranyloxy)butyl)valerolactam 
• 154656-91-4 N-(3-hydroxybutyl)valerolactam 
• 154656-92-5 N-(3-oxobutyl)valerolactam 
• 82360-25-6 N-(3-carbethoxypropyl)-2-piperidinone 

Downstream Products

• 13618-93-4 indolizidine 

Relevant academic research and scientific papers

Enamines and iminium salts from amino-acids

Distillation of ω-carboxyalkyl lactams from soda-lime leads to the formation of bicyclic enamines or imines with concomitant loss of carbon dioxide and water.Monoamides of dicarboxylic acids afford cyclic ketones.A mechanistic rationale is presented and it is concluded that the reaction is a variant of the classical Ruzicka cyclization of dicarboxylic acids.The method allows the regiospecific formation of iminium salts of bicyclic nitrogen heterocycles.

AZAPROPELLANES AS PHASE-TRANSFER CATALYSTS-II A CMR AND PMR STUDY OF THE THREE-DIMENSIONAL STRUCTURE OF 1-AZONIAPROPELLANES CONTAINING 5- AND 6-MEMBERED RINGS

An improved synthesis of 1-azoniatricyclo1,6>tridecane (2) and the preparation of the remaining member of the series, 1-azoniatricyclo1,6>dodecane salts (3) have been achieved.Using a combination of 1H (at 400 MHz) and 13C NMR spectra has allowed the assignment of the signals in the well-resolved 1H spectra.The results indicate that 1 exists in the all-chair form which undergoes racemisation by ring inversion with a rate constant of 0.7 sec-1 and further that the counterion in these salts is restricted to associating with only one face of the tetrahedral N atom.

Synthesis of Δ1- and/or Δ8-Dehydroindolizidines and Related Compounds

A facile synthesis of Δ1- and/or Δ8-dehydroindolizidine and related compounds, consisting of dry distillation of γ-(N-2-piperidinonyl)butyric acid over soda-lime, is described.Reductions of these dehydroindolizidines and stereochemistry of 1-methylindolizidine are also described.