82365-89-7Relevant academic research and scientific papers
TAUTOMERISM IN THE SERIES OF PRODUCTS FROM THE CONDENSATION OF AROYLACETONES WITH AROYLHYDRAZINES
Yakimovich, S. I.,Nikolaev, V. N.,Kutsenko, E. Yu.
, p. 662 - 669 (2007/10/02)
By PMR spectroscopy it was shown that the products from the condensation of aroylacetones with aroylhydrazines in (dimethyl sulfoxide)-d6 solution exist as tautomeric mixtures of the ketoenamine and cyclic 5-hydroxypyrazoline forms.The introduction of electron-withdrawing substituents into the aromatic ring of the N-aroyl radical and into the aromatic ring at the carbon atom of the carbonyl function shifts the tautomeric equilibrium toward the cyclic 5-hydroxy-pyrazoline form.The above-mentioned substituents have an independent effect on the position of the ring-chain tautomeric equilibrium.
