823804-73-5

Basic information

• Product Name: 1,3-Benzenediol, 5-[(1E)-2-cyclohexylethenyl]- (9CI)
• Synonyms: 1,3-Benzenediol, 5-[(1E)-2-cyclohexylethenyl]- (9CI)
• CAS NO: 823804-73-5
• Molecular Formula: C₁₄H₁₈O₂
• Molecular Weight: 218.29152
• Product Categories: ALCOHOL
• Mol File: 823804-73-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Benzenediol, 5-[(1E)-2-cyclohexylethenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenediol, 5-[(1E)-2-cyclohexylethenyl]- (9CI)(823804-73-5)
• EPA Substance Registry System: 1,3-Benzenediol, 5-[(1E)-2-cyclohexylethenyl]- (9CI)(823804-73-5)

Safety Data

• Hazardous Substances Data: 823804-73-5(Hazardous Substances Data)

Usage

Type of compound

Derivative of benzenediol

Structural feature

Cyclohexylethenyl group attached to the 5th position of the benzene ring

Common uses

Production of various industrial products, research field

Potential applications

Pharmaceutical and cosmetics industries

Safety considerations

Handle with care, hazardous properties, use and store in accordance with safety guidelines

Upstream product

• 695-12-5 vinylcyclohexane 
• 39192-49-9 3,5-diacetoxybenzoyl chloride 

Relevant articles and documents

Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor

A series of 31 resveratrol derivatives was designed, synthesized and evaluated for activation and inhibition of the TRPA1 channel. Most acted as activators and desensitizers of TRPA1 channels like resveratrol or allyl isothiocyanate (AITC). Compound 4z (HUHS029) exhibited higher inhibitory activity than resveratrol with an IC50 value of 16.1?μM. The activity of 4z on TRPA1 was confirmed in TRPA1-expressing HEK293 cells, as well as in rat dorsal root ganglia neurons by a whole cell patch clamp recording. Furthermore, pretreatment with 4z exhibited an analgesic effect on AITC-evoked TRPA1-related pain behavior in vivo.