82386-90-1

Basic information

• Product Name: (5-CHLORO-2-IODOPHENYL)METHANOL
• Synonyms: (5-CHLORO-2-IODOPHENYL)METHANOL;5-CHLORO-2-IODOBENZYL ALCOHOL;5-Chloro-2-iodobenzenemethanol;BenzeneMethanol, 5-chloro-2-iodo-
• CAS NO: 82386-90-1
• Molecular Formula: C₇H₆ClIO
• Molecular Weight: 268.48
• Mol File: 82386-90-1.mol
• Article Data: 19

Chemical Properties

• Melting Point: 102-104℃
• Boiling Point: 316℃
• Flash Point: 145℃
• Appearance: /
• Density: 1.955
• CAS DataBase Reference: (5-CHLORO-2-IODOPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (5-CHLORO-2-IODOPHENYL)METHANOL(82386-90-1)
• EPA Substance Registry System: (5-CHLORO-2-IODOPHENYL)METHANOL(82386-90-1)

Safety Data

• Hazardous Substances Data: 82386-90-1(Hazardous Substances Data)

Usage

General Description

(5-Chloro-2-iodophenyl)methanol is a chemical compound containing a benzene ring with a chlorine and iodine atom attached to it, as well as a hydroxyl group. It is primarily used as an intermediate in the synthesis of a variety of pharmaceutical and agrochemical products. (5-CHLORO-2-IODOPHENYL)METHANOL has potential applications in the development of medicines, as well as in the production of pesticides and herbicides. Additionally, it may have uses in various chemical reactions in the laboratory setting. The presence of both a halogen and a hydroxyl group in its structure gives (5-chloro-2-iodophenyl)methanol unique reactivity and potential for further functionalization in organic synthesis. Overall, this chemical has promising potential for the pharmaceutical and agricultural industries due to its versatile reactivity and applications.

Upstream product

• 13421-00-6 5-chloro-2-iodo-benzoic acid 
• 635-21-2 5-chloroanthranilic acid 
• 82386-96-7 2-Chloro-11-H-dibenz-1,4-oxathiepin 
• 121-43-7 Trimethyl borate 
• 15396-37-9 2-iodoyl-3,5-dichlorobenzoic acid 

Downstream Products

• 439117-17-6 (2-azetidin-2-yl-5-chlorophenyl)methanol hydrochloride 
• 439115-48-7 1-((2R)-2-Cyclohexyl-2-hydroxyethanoyl)-N-(2-(1-amino-2,2-difluoroethyl)-5-chlorobenzyl)-L-prolinamide 

Relevant articles and documents

COMPOUNDS HAVING BOTH EFFECTS OF BET BROMODOMAIN PROTEIN INHIBITION AND PD-L1 GENE REGULATION

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CuSO4-Catalyzed dual annulation to synthesize O, S or N-containing tetracyclic heteroacenes

In this work, CuSO4 is utilized as a practical redox catalyst for tandem dual annulation in the synthesis of indole-fused tetracyclic heteroacenes, which are important skeletons in both medicinal chemistry and materials chemistry. The preparation of such skeletons in a convenient and efficient manner is in high demand. This method realizes the modular synthesis of benzofuro-, benzothieno-, and indoloindoles from abundant feedstocks such as 2-halobenzyl halides and nitrile derivatives in up to 99% yields, providing a rapid access to diverse indole-fused heteroacenes with biological or optoelectronic properties.

Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction

A palladium-catalyzed enantioselective coupling of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles is described. The reaction proceeded via a tandem asymmetric Heck insertion and Tsuji-Trost allylation, enabling the rapi