82387-34-6

Basic information

• Product Name: (E)-3-(3-Benzyl-ureido)-2-methyl-acrylic acid methyl ester
• Synonyms: (E)-3-(3-Benzyl-ureido)-2-methyl-acrylic acid methyl ester
• CAS NO: 82387-34-6
• Molecular Weight: 248.282
• Mol File: 82387-34-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-(3-Benzyl-ureido)-2-methyl-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(3-Benzyl-ureido)-2-methyl-acrylic acid methyl ester(82387-34-6)
• EPA Substance Registry System: (E)-3-(3-Benzyl-ureido)-2-methyl-acrylic acid methyl ester(82387-34-6)

Safety Data

• Hazardous Substances Data: 82387-34-6(Hazardous Substances Data)

Upstream product

• 82387-42-6 Methyl 3-methoxy-2-methyl-2-propenoate 
• 538-32-9 benzylurea 

Downstream Products

• 21473-22-3 3-benzyl-5-methyl-2,4(1H)-pyrimidinedione 
• 51673-64-4 methyl 2-methyl-3-oxopropanoate 
• 538-32-9 benzylurea 

Relevant articles and documents

SYNTHESIS OF METHYL 3-(N'-ALKYLUREIDO)-2-METHYL-2-PROPENOATES AND THEIR CYCLIZATION TO 3-ALKYL-5-METHYLURACILS

Stereoisomeric methyl 3-(N'-alkylureido)-2-methyl-2-propenoates (Ia-Id) were prepared by acid-catalyzed reaction of N-alkylureas (R = methyl, benzyl, isopropyl and tert-butyl) with methyl 3-methoxy-2-methyl-2-propenoate (III).Reaction of the ester III with N-tert-butylthiourea afforded the thioureides (E)-Ie and (Z)-Ie.On treatment with sodium methoxide in methanol, compounds Ia-Ic cyclized to the corresponding 3-alkyl-5-methyluracils IIa-IIc whereas compounds Id and Ie underwent only a base catalyzed E/Z isomerization with (E)-isomers predominating.