82387-87-9

Basic information

• Product Name: 5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-
• Synonyms: 5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-
• CAS NO: 82387-87-9
• Molecular Formula: C₁₀H₈N₂O₄
• Molecular Weight: 0
• Mol File: 82387-87-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-(82387-87-9)
• EPA Substance Registry System: 5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-(82387-87-9)

Safety Data

• Hazardous Substances Data: 82387-87-9(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 76765-75-8 rac-ethyl 2-(4-nitrobenzamido)propanoate 
• 122-04-3 4-nitro-benzoyl chloride 
• 302-72-7 rac-Ala-OH 
• 5330-84-7 rac-2-(4-nitrobenzamido)propanoic acid 

Downstream Products

• 1423044-86-3 (R)-4-methyl-2-(4-nitrophenyl)-4-((R)-3-oxo-1-phenylbutyl)oxazol-5(4H)-one 
• 1246184-11-1 (1R,2S,5S)-2-methyl-3-(4-nitrobenzoyl)-4-oxo-3-azabicyclo[3.2.0]hept-6-ene-2-carboxylic acid 
• 1356686-66-2 C₁₅H₁₄N₂O₇ 
• 1273544-79-8 C₁₉H₁₉N₃O₆S 
• 1228801-85-1 1,2-bis(ethoxycarbonyl)-3-methyl-5-(4-nitrophenyl)-2,3-dihydro-1H-1,2,4-triazole-3-carboxylic acid 

Relevant articles and documents

Group-Assisted Purification Chemistry for Asymmetric Mannich-type Reaction of Chiral N-Phosphonyl Imines with Azlactones Leading to Syntheses of α-Quaternary α,β-Diamino Acid Derivatives ?

An asymmetric Mannich-type reaction between chiral N-phosphonyl imines and azlactones [oxazol-5(4H)-ones] has been established under convenient conditions at room temperature. The reaction was performed without using any bases, additives, or catalysts to achieve up to excellent chemical yields and diastereoselectivity for 32 examples. The α-quaternary syn-α,β-diamino acid products were purified simply by washing the crude mixtures with cosolvents, following the group-assisted purification chemistry/technology, without involving traditional chromatography or recrystallization methods. The auxiliary can be readily removed and recycled for reuse. The absolute configuration was unambiguously assigned by X-ray structural analysis.

Synthesis of 1,2,4-Triazolines and triazoles utilizing oxazolones

We describe herein a convenient method for the synthesis of 1,2,4-triazolines using oxazolones and azodicarboxylates. Subsequent treatment of these 1,2,4-triazolines with NaOH provides efficient access to the corresponding triazoles.

Studies on chromone derivatives : An efficient one-pot synthesis of various 3-( N-aroylamino)-3-methyl-4-(4-oxobenzopyran-3-yl)-1-( N,N-dimethylamino)azetidin-2-ones

Chlorosulfonylmethylene(dimethyl)ammonium chloride 1 is found to be a highly reactive cyclodehydrating agent for the one-pot synthesis of various novel 3-(N-aroylamino)-3-methyl-4-(4-oxobenzopyran-3-yl)-1-(N,N-dimethylamino) azetidin-2-ones 5 from N-aroyl