82413-57-8

Basic information

• Product Name: 2-(Formylamino)butanoic acid
• Synonyms: FOR DL-ABU(2)-OH;FORMYL-DL-2-AMINO-N-BUTYRIC ACID;ALPHA-N-FORMYL-DL-2-AMINO-N-BUTYRIC ACID;N-FORMYL-DL-2-AMINO-N-BUTYRIC ACID;Formylaminobutyricacid (alpha-);N-Formyl-DL-2-amino-n-butyric acid (alpha-);N-Formyl-DL-2-aminobutyric Acid;2-(Formylamino)butanoic acid
• CAS NO: 82413-57-8
• Molecular Formula: C5H9NO3
• Molecular Weight: 131.13
• Mol File: 82413-57-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 367.6 °C at 760 mmHg
• Flash Point: 176.1 °C
• Appearance: /
• Density: 1.168 g/cm³
• Vapor Pressure: 2.07E-06mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: 2-(Formylamino)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Formylamino)butanoic acid(82413-57-8)
• EPA Substance Registry System: 2-(Formylamino)butanoic acid(82413-57-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-36
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 82413-57-8(Hazardous Substances Data)

Usage

General Description

2-(Formylamino)butanoic acid, also known as 2-amino-4-formylbutanoic acid, is an organic compound with the molecular formula C5H9NO3. It is an α-amino acid, meaning it contains both an amine group and a carboxylic acid group. 2-(Formylamino)butanoic acid is a derivative of butanoic acid, with an additional formylamino group attached to the second carbon atom. It is a white crystalline solid that is soluble in water. 2-(Formylamino)butanoic acid is not commonly found in nature, but it can be synthesized for use in chemical research and pharmaceutical applications. Its chemical properties make it an important intermediate in the production of various compounds, including some pharmaceuticals and agrochemicals.

InChI:InChI=1/C5H9NO3/c1-2-4(5(8)9)6-3-7/h3-4H,2H2,1H3,(H,6,7)(H,8,9)

Upstream product

• 64-18-6 formic acid 
• 2835-81-6 2-aminobutanoic acid 
• 2623-91-8 (R)-2-aminobutyric acid 

Relevant articles and documents

Synthesis of chiral pentacyclo-undecane ligands and their use in the enantioselective alkylation of benzaldehyde with diethylzinc

The synthesis of a new class chiral cage annulated bidentate ligands is reported. The ability of the chiral amino alcohols to catalyse the enantioselective addition of diethyl zinc to benzaldehyde was investigated. The cage annulated amino alcohols have C1 symmetry and showed poor to good enantioselectivity with high chemical yields. The system could be utilised as a versatile probe into the reaction mechanism. The synthesis of a new class of chiral pentacycloundecane cage annulated bidentate ligands is reported. This class of ligands can be used in many reactions that are catalysed by amino alcohol ligands. The ability of the chiral ligands to asymmetrically catalyse the reaction between diethylzinc and benzaldehyde was investigated. The cage annulated bidentate ligands have C1 symmetry and showed poor to good enantioselectivity with high yields compared to previous systems reported using other amino alcohol ligands. An important conclusion from the results is that both ligands should be involved in the mechanism as the bidentate ligands gives much improved enantioselectivity when compared with a single chiral source molecule. This system could be utilised as a versatile probe for examining the reaction mechanism.