82414-34-4

Basic information

• Product Name: 1-methyl-3-chloroindol-2-carboxanilide
• CAS NO: 82414-34-4
• Molecular Weight: 284.745
• Mol File: 82414-34-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-methyl-3-chloroindol-2-carboxanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-3-chloroindol-2-carboxanilide(82414-34-4)
• EPA Substance Registry System: 1-methyl-3-chloroindol-2-carboxanilide(82414-34-4)

Safety Data

• Hazardous Substances Data: 82414-34-4(Hazardous Substances Data)

Upstream product

• 1025-99-6 (1-methyl-1H-indol-2-yl)(phenyl)methanone 
• 82414-27-5 (1-Methyl-1H-indol-2-yl)-phenyl-methanone oxime 
• 39167-76-5 N-phenyl-1-methyl-1H-indole-2-carboxamide 

Relevant articles and documents

SELECTIVITY IN CYCLOADDITIONS-IX CYCLOADDITIONS OF NITRILE OXIDES TO INDOLES. REACTIVITY AND REGIOCHEMISTRY

Cycloadditions of benzonitrile oxide and mesitonitrile oxide to N-methylindole and indole yield the acid sensitive cycloadducts 1 a-d with high regioselectivity.With N-carbethoxyindole the stable cycloadducts 1 e,f and minor amounts of the regioisomeric 2 e,f are isolated.The electron withdrawing substituent reduces both the regioselectivity and the reactivity of the cycloadditions.Frontier orbital considerations, based on MINDO/3 calculations, allow elucidation of the observed changes in reactivity and regiochemistry.