1025-99-6

Basic information

• Product Name: 2-Benzoyl-1-methyl-1H-indole
• Synonyms: 2-Benzoyl-1-methyl-1H-indole
• CAS NO: 1025-99-6
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• Mol File: 1025-99-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Benzoyl-1-methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzoyl-1-methyl-1H-indole(1025-99-6)
• EPA Substance Registry System: 2-Benzoyl-1-methyl-1H-indole(1025-99-6)

Safety Data

• Hazardous Substances Data: 1025-99-6(Hazardous Substances Data)

Upstream product

• 157427-47-9 N-Methyl-2-benzylindole 
• 100-52-7 benzaldehyde 
• 603-76-9 1-methylindole 
• 156571-69-6 N-methoxy-N-methyl-1H-indole-2-carboxamide 
• 548489-89-0 N-methoxy-N-methyl-1-methylindole-2-carboxamide 
• 591-51-5 phenyllithium 
• 1477-50-5 Indole-2-carboxylic acid 
• 1022-86-2 2-benzoylindole 
• 74-88-4 methyl iodide 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 108-86-1 bromobenzene 

Downstream Products

• 799821-92-4 methyl 9-methyl-1-phenyl-9H-pyrido[3,4-b]indole-3-carboxylate 
• 1373438-32-4 (E)-5-bromo-2-hydroxy-N'-((1-methyl-1H-indol-2-yl)(phenyl)methylene)benzohydrazide 
• 1373438-33-5 C₂₃H₁₈BrN₃O₂ 
• 1334532-38-5 C₂₃H₂₀N₂O₂S 
• 82414-34-4 1-methyl-3-chloroindol-2-carboxanilide 
• 82414-27-5 (1-Methyl-1H-indol-2-yl)-phenyl-methanone oxime 
• 82414-27-5 (1-Methyl-1H-indol-2-yl)-phenyl-methanone oxime 
• 53278-22-1 (3-acetoxy-1-methyl-indol-2-yl)-phenyl-methanone 

Relevant articles and documents

One-Pot Assembly of 3-Hydroxycarbazoles via Uninterrupted Propargylation/Hydroxylative Benzannulation Reactions

A novel strategy for the synthesis of 3-hydroxycarbazoles involving the consecutive propargylation/palladium-catalyzed hydroxylative benzannulation of indole-2-carbonyls with propargylic alcohols has been exploited. This one-pot procedure leads to a wide range of substituted 3-hydroxycarbazoles in high yield with a broad substrate scope. The method was further extended to access furano-carbazole derivatives from dialkynols via tandem annulations.

Syntheses of 1-alkyl-2-acylindoles, 1-alkyl-2-acylindole-3-carboxylic acids, and their esters, in superbasic media

2-Acylindoles and 2-acylindole-3-carboxylic acids are readily alkylated at the nitrogen atom by haloalkanes in a superbasic medium (DMSO + NaOH). For the carboxylic acids, this reaction may proceed either entirely at the nitrogen atom, or at both the the

Oxidation of Indoles with Lead Tetra-acetate and Hydrolysis of 1,2-Disubstituted Indol-3-yl Acetates

Oxidation of some 1,2-disubstituted indoles with lead tetra-acetate gives the corresponding 3-acetoxy derivatives.Similar oxidation of ethyl indole-2-carboxylate affords an acetoxylated 3,3'-bi-indolyl product; methyl 1-methylindol-3-yl acetate is acetoxylated at the benzylic position of the side-chain.Alkaline hydrolysis of 1,2-disubstituted indol-3-yl acetates is accompanied by autoxidation and rearrangement to give dioxindoles, but hydrolysis of 2-ethoxycarbonyl-1-methylindol-3-yl acetate gives N,N'-dimethyl derivatives of indigo and indirubin.