82423-69-6Relevant academic research and scientific papers
Copper-catalyzed Ficini [2 + 2] cycloaddition of ynamides
Li, Hongyan,Hsung, Richard P.,Dekorver, Kyle A.,Wei, Yonggang
supporting information; experimental part, p. 3780 - 3783 (2010/10/21)
The Ficini [2 + 2] cycloaddition using N-sulfonyl-substituted ynamides is described, featuring the utility of CuCl2 and AgSbF6 as catalysts. This work represents the first successful example of ynamides participating in a thermal [2 + 2] cycloaddition with enones.
Addition of Ketene Trimethylsilyl Acetals to α,β-Unsaturated Ketones: A New Strategy for Michael Addition of Ester Enolates
RajanBabu, T. V.
, p. 2083 - 2089 (2007/10/02)
Trialkylsilyl ketene acetals in the presence of tris(dimethylamino)sulfonium difluorotrimethylsiliconate generate very potent carbon nucleophiles formally equivalent to ester enolates.In sharp contrast to the commonly used lithium enolates, these acetals
Keten Silyl Acetal Chemistry; Simple Synthesis of Methyl Jasmonate and Related Compounds by Utilising Keten Methyl Dimethyl-t-butylsilyl Acetal
Kita, Yasuyuki,Segawa, Jun,Haruta, Jun-ichi,Yasuda, Hitoshi,Tamura, Yasumitsu
, p. 1099 - 1104 (2007/10/02)
Conjugate addition of keten silyl acetals to α,β-unsaturated carbonyl compounds in acetonitrile gave a quantitative yield of the corresponding methyl (3-trialkylsiloxyalk-2-enyl)acetates; subsequent site-specific electrophilic substitution yielded the corresponding 2-substituted 3-(alkoxycarbonylmethyl)alkanones.These novel addition and sequential alkylation reactions could be applied to a simple synthesis of methyl jasmonate, methyl didehydrojasmonate, and methyl dihydrojasmonate.
O-silylated ketene acetal chemistry; β-(alkoxycarbonyl)methyl O-silyl enolates, useful synthons for α-substituted-β-(alkoxycarbonyl)methylalkanones
Kita,Segawa,Haruta,Fujii,Tamura
, p. 3779 - 3782 (2007/10/02)
Conjugate addition of O-silylated ketene acetals 2 to α,β-unsaturated carbonyl compounds 1 in acetonitrile gave quantitative yields of the corresponding β-(alkoxycarbonyl)methyl O-silyl enolates 4. Site specific electrophilic substitutions of 4 yielded th
