82427-16-5

Basic information

• Product Name: 2-methyl-1-(o-tolyl)butan-1-one
• Synonyms: 2-methyl-1-(o-tolyl)butan-1-one
• CAS NO: 82427-16-5
• Molecular Weight: 176.258
• Mol File: 82427-16-5.mol

Chemical Properties

• CAS DataBase Reference: 2-methyl-1-(o-tolyl)butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1-(o-tolyl)butan-1-one(82427-16-5)
• EPA Substance Registry System: 2-methyl-1-(o-tolyl)butan-1-one(82427-16-5)

Safety Data

• Hazardous Substances Data: 82427-16-5(Hazardous Substances Data)

Upstream product

• 142509-27-1 5-(1-methylpropyl)-1-aza-5-stannabicyclo[3.3.3]undecane 
• 933-88-0 ortho-toluoyl chloride 

Relevant articles and documents

Stereospecific Palladium-Catalyzed Acylation of Enantioenriched Alkylcarbastannatranes: A General Alternative to Asymmetric Enolate Reactions

We report the development of a Pd-catalyzed process for the cross coupling of unactivated primary, secondary, and tertiary alkylcarbastannatrane nucleophiles with acyl electrophiles. Reactions involving optically active alkylcarbastannatranes occur with exceptional stereofidelity and with net retention of absolute configuration. Because the stereochemistry of the resulting products is entirely reagent-controlled, this process may be viewed as a general, alternative approach to the preparation of products typically accessed via asymmetric enolate methodologies. Additionally, we report a new method for the preparation of optically active alkylcarbastannatranes, which should facilitate their future use in stereospecific reactions.