82434-61-5Relevant academic research and scientific papers
Activation of murine RNase L by isopolar 2′-phosphonate analogues of 2′,5′ oligoadenylates
Pav, Ondrej,Protivinska, Eva,Pressova, Martina,Collinsova, Michaela,Jiracek, Jiri,Snasel, Jan,Masojidkova, Milena,Budesinsky, Milos,Rosenberg, Ivan
, p. 3955 - 3962 (2007/10/03)
To determine the influence of methylene group insertion in the internucleotide linkage on the binding process of 2′,5′- oligoadenylates to RNase L, a series of 2′-phosphonate-modified trimers and tetramers were synthesized from appropriate monomeric units
Ribo-, Xylo-, and Arabino-configured adenine-based nucleoside phosphonates: Synthesis of monomers for solid-phase oligonucleotide assembly
Pav, Ondrej,Budesinsky, Milos,Rosenberg, Ivan
, p. 1053 - 1056 (2007/10/03)
Adenine-based, regioisomeric nucleoside phosphonates with ribo, xylo and arabino configuration were synthesized in the protected form suitable for the phosphotriester-like, solid-phase synthesis of oligonucleotides. Phosphonate moiety was protected by 4-m
New catalists and procedures for the dimethoxytritylation and selective silylation of ribonucleosides
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 1106 - 1113 (2007/10/02)
Procedures have been developed for the selective formation of (a) 2',5'-silylated ribonucleosides and (b) 3',5'-silylated ribonucleosides.These procedures also permit the selective silylation at either the 2'- or 3'-position of dimethoxytritylated ribonuc
