82477-48-3Relevant academic research and scientific papers
PREPARATION OF ESTERS CONTAINING AN Α-CF3 GROUP
Purrington, Suzanne, T.,Everett, T. Stephen,Bumgardner, Carl L.
, p. 1329 - 1332 (2007/10/02)
Malonates may be converted to esters containing an α-CF3 group in a two-step process involving bromodifluoromethylation of the malonates followed by decarboxyalkylation-fluorination with fluoride ion in DMSO.
Preparation of α-Trifluoromethyl Esters from Malonic Esters
Everett, Stephen T.,Purrington, Suzanne T.,Bumgardner, Carl L.
, p. 3702 - 3706 (2007/10/02)
A wide variety of α-trifluoromethyl esters can be synthesized in two steps starting from monosubstituted malonic esters and dibromodifluoromethane.The product of the first step, a bromodifluoromethyl-substituted malonate, is transformed to the desired fin
Reactivity of the Perhalogenoalkanes CF2BrX (X = Cl, Br) with Nucleophiles. Part 4. Condensation with Carbanions
Rico, Isabelle,Cantacuzene, Danielle,Wakselman, Claude
, p. 1063 - 1066 (2007/10/02)
The condensation of CF2BrX (X = Cl, Br) with different carbanions is described.CF2BrX reacts with lithium acetylides and with substituted, active methylene compounds.The limits of reactivity of this reagent as well as the mechanism involved in the condens
