82486-43-9

Basic information

• Product Name: 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME
• Synonyms: 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME;2-Hydroxy-5-bromobenzaldehyde oxime;5-Bromosalicylaldehyde oxime;5-Bromosalicylaldoxime;4-bromo-2-[(1E)-(hydroxyimino)methyl]phenol
• CAS NO: 82486-43-9
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• Mol File: 82486-43-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 278.9°C at 760 mmHg
• Flash Point: 122.5°C
• Appearance: /
• Density: 1.983g/cm³
• Vapor Pressure: 0.000503mmHg at 25°C
• Refractive Index: 1.79
• CAS DataBase Reference: 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME(82486-43-9)
• EPA Substance Registry System: 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME(82486-43-9)

Safety Data

• Hazardous Substances Data: 82486-43-9(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-hydroxybenzaldehyde oxime is a chemical compound with the molecular formula C7H6BrNO2. It is a pale yellow solid with a molecular weight of 214.03 g/mol. 5-BROMO-2-HYDROXYBENZALDEHYDE OXIME is commonly used as a building block in organic synthesis and as a reagent in chemical reactions. Its primary function is to act as a chelating agent for metal ions in complexation reactions. It is also used in pharmaceutical research for the development of new drugs and in the production of agricultural chemicals. Additionally, 5-Bromo-2-hydroxybenzaldehyde oxime is utilized in the manufacturing process of dyes and other industrial chemicals.

InChI:InChI=1/C7H6BrNO2/c8-6-1-2-7(10)5(3-6)4-9-11/h1-4,9,11H/b5-4+

Upstream product

• 1761-61-1 5-bromosalicyclaldehyde 
• 2316-64-5 5-bromo-2-hydroxybenzyl alcohol 

Downstream Products

• 89-55-4 5-bromosalicyclic acid 
• 1761-61-1 5-bromosalicyclaldehyde 
• 837392-65-1 5-bromo-1,2-benzoisoxazole 
• 422310-78-9 (C₆H₅)4SbONCHC₆H₃(OH)-2-Br-5 
• 6329-74-4 5-bromo-2-hydroxybenzamide 
• 40530-18-5 5-bromo-2-hydroxybenzonitrile 
• 862672-11-5 triphenylantimony bis(5-bromo-2-hydroxybenzaldoximate) 
• 422310-83-6 (C₆H₄(Me)-4)4SbONCHC₆H₃(OH)-2-(Br)-5 
• 2199-94-2 6-bromo-2-oxo-2H-1-benzopyran-3-carboxylic acid chloride 

Relevant articles and documents

Solvent-Dependent Oxime-Azide and Oxime-Nitrile Coupling: Crystallographic and Catalytic Studies

This study describes the solvent-dependent conversion of an oxime under identical reaction conditions ([Cu(bipy)Cl2]/NaN3/5-Br-H2salox/TEA=1:2:1:2 molar ratio; bipy=2,2′-bipyridyl, 5-Br-H2salox=5-bromosalicylaldoxime, TEA=triethylamine), but in different solvents. In DMSO/CH2Cl2 (2:1v/v) only tetrazole is formed, whereas iminoacylation in MeCN and simple complexation takes place in MeOH. The formed tetrazole and iminoacylated ligands further undergo complexation with metal ions, as evidenced from single-crystal X-ray diffraction studies and ESI-MS analyses. Mechanistic models have been proposed in which coordination-assisted bonding of sodium azide across the -C=N-OH double bond occurs to form a tetrazole and oxime-MeCN coupling forms an iminoacylated ligand. The former is a catalytic reaction, as evidenced from a turnover number of approximately 50, whereas the latter is stoichiometric in nature. This is the first report to demonstrate the dependence of solvent polarity on oxime transformation reactions through structural elucidation.

Compounds For The Treatment Of Neuromuscular Disorders

The present invention relates to compounds suitable for treating, ameliorating and/or preventing neuromuscular disorders, including the reversal of drug-induced neuromuscular blockade. The compounds as defined herein preferably inhibit the ClC-1 ion chann

Calculation and experimental measurement of paramagnetic NMR parameters of phenolic oximate Cu(II) complexes

We present a strategy for predicting the unusual 1H and 13C shifts in NMR spectra of paramagnetic bisoximato copper(ii) complexes using DFT. We demonstrate good agreement with experimental measurements, although 1H-13C correlation spectra show that a combined experimental and theoretical approach remains necessary for full assignment.