824932-90-3Relevant academic research and scientific papers
PYRROLIDINE DERIVATIVES AS PPAR AGONISTS
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Paragraph 0125; 0128; 0129, (2019/08/02)
The present invention discloses a class of pyrrolidine derivatives as PPAR agonist, and their use for the treatment of some diseases of PPAR receptor-associated pathways (such as nonalcoholic steatohepatitis and concurrent fibrosis, insulin resistance, primary biliary cholgangitis, dyslipidenmia, hyperlipidemia, hypercholesterolemia, atherosclerosis, hypertriglyceridemia, cardiovascular disease, obesity or the like). In particular, the present invention discloses a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
GFT505 and preparation method for intermediate thereof
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Paragraph 0041; 0042; 0043; 0044; 0045, (2017/08/29)
The invention discloses GFT505 and a preparation method for an intermediate thereof. The invention provides the preparation method for an intermediate I of GFT505, comprising the following steps: in an organic solvent, carrying out isomerization reaction
IMPROVED PREPARATION OF CHALCONE DERIVATIVES
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Page/Page column 24-25, (2011/12/04)
The invention relates to methods for producing chalcone (1,3-diphenylprop-2-en-1 -one) derivatives that have multiple substitutions on a phenyl ring. Intermediate chalcone derivatives are modified by Phase Transfer Catalysis (PTC) for introducing a substi
