824952-29-6

Upstream product

• 579-43-1 (1S,2R)-1,2-diphenylethane-1,2-diol 
• 108031-80-7 (2S,2'S-(2α,2'α,3aα,3a'α,4β,4'β,7β,7'β,7aα,7a'α))-2,2'-oxybis[octahydro-7,8,8-trimethyl-4,7-methanobenzofuran] 

Downstream Products

• 866456-89-5 [2S-(2α(1R*,2S*),3aα,4β,7β,7aα)]-[2-[(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy]-1,2-diphenylethoxy]acetic acid 1,1-dimethylethyl ester 
• 866456-87-3 [2S-(2α(1S*,2R*),3aα,4β,7β,7aα)]-2-[2-(2-methylpropoxy)-1,2-diphenylethoxy]octahydro-7,8,8-trimethyl-4,7-methanobenzofuran 
• 1237738-33-8 C₃₄H₄₀O₄ 
• 118298-93-4 (+)-erythro-α,β-diphenyl-β-hydroxyethanol benzyl ether 
• 870298-18-3 [2S-(2α(1S*,2R*),3aα,4β,7β,7aα)]-2-[2-(2-methoxy-2,2-diphenylethoxy)-1,2-diphenylethoxy]octahydro-7,8,8-trimethyl-4,7-methanobenzofuran 
• 870298-16-1 [2S-(2α(1R*,2S*),3aα,4β,7β,7aα)]-2-[2-[(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy]-1,2-diphenylethoxy]-1,1-diphenylethanol 
• 866456-91-9 [2S-(2α(1R*,2S*),3aα,4β,7β,7aα)]-2-[2-[(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy]-1,2-diphenylethoxy]propionic acid 1,1-dimethylethyl ester 
• 870298-24-1 oxo-phenylacetic acid (1R,2S)-2-(2-methoxy-2,2-diphenylethoxy)-1,2-diphenylethyl ester 
• 870298-15-0 [2S-(2α(1R*,2S*),3aα,4β,7β,7aα)]-2-[2-[(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy]-1,2-diphenylethoxy]ethanol 
• 870298-17-2 [2S-(2α(1S*,2R*),3aα,4β,7β,7aα)]-2-[2-(2-methoxyethoxy)-1,2-diphenylethoxy]octahydro-7,8,8-trimethyl-4,7-methanobenzofuran 
• 866457-07-0 oxophenylacetic acid (1R,2S)-2-benzyloxy-1,2-diphenylethyl ester 
• 870298-25-2 oxo-phenylacetic acid (1R,2S)-2-(2-dimethylaminoethoxy)-1,2-diphenylethyl ester 
• 870298-26-3 3-oxo-3-phenylpropionic acid (1R,2S)-2-(2-methoxyethoxy)-1,2-diphenylethyl ester 

Relevant academic research and scientific papers

Application of meso-hydrobenzoin-derived chiral auxiliaries for the stereoselective synthesis of highly substituted pyrrolidines by 1,3-dipolar cycloaddition of azomethine ylides

The metal-catalyzed stereoselective 1,3-dipolar cycloaddition of azomethine ylides and acrylates using recyclable meso-hydrobenzoin-derived chiral auxiliaries is described. Cleavage of the auxiliary leads to highly substituted pyrrolidines in up to 87% en

Synthesis of novel chiral hydrobenzoin mono-tert-butyl ethers derived from m-hydrobenzoin and their application as chiral auxiliaries in the diastereoselective reduction of α-keto esters

Three m-hydrobenzoin derived chiral hydrobenzoin mono-tert-butyl ethers were synthesized by a new reaction pathway and tested as chiral auxiliaries in the L-selectride mediated stereoselective reduction of their corresponding phenyl glyoxylates. As a result, improved stereoselectivities of up to a ratio of 92:8 compared to 84:16 with the initially examined analogous benzyl ether were achieved.