824975-93-1Relevant academic research and scientific papers
Bis(triphenylphosphine)palladium(II)phthalimide - An easily prepared precatalyst for efficient Suzuki-Miyaura coupling of aryl bromides
Chaignon, Nicholas M.,Fairlamb, Ian J.S.,Kapdi, Anant R.,Taylor, Richard J.K.,Whitwood, Adrian C.
, p. 191 - 199 (2004)
In this paper we report the synthesis and application of a novel palladium(II) complex, bis(triphenylphosphine)palladium(II)phthalimide 1. Its utility in the Suzuki-Miyaura coupling of aryl bromides with a variety of aryl- and heteroarylboronic acids, under relatively mild conditions, is described. Complex 1 is easily prepared from tetrakis(triphenylphosphine)palladium(0) and phthalimide in 78% yield and is air, light and moisture stable. On following the kinetics of the cross-coupling reaction of 4-nitro-1-bromobenzene with phenylboronic acid, mediated by 1 (1 mol%) in THF/aqueous 1 M Na 2CO3 (1/1, v/v) at 60°C, an initial induction period is observed, indicating that 1 is a precatalyst. The described work extends on our recent finding that 'imidate' type ligands have an influence in palladium-catalysed cross-coupling processes.
Bis(imidate)palladium(ii) complexes with labile ligands. Mimics of classical precursors?
Sanchez, Gregorio,Garcia, Joaquin,Martinez, Marina,Kapdi, Anant R.,Perez, Jose,et al.
, p. 12676 - 12689 (2012/03/22)
A novel synthetic route to prepare palladium(ii) precursor analogous of classical [Pd(Cl)2(solvent)2] has been developed. Just stirring Pd3(AcO)6 in dimethyl sulfide at room temperature, in the stoichiometric pr
