82500-59-2

Upstream product

• 95539-28-9 2-thio-5-(o-nitrobenzyl)-6-azauracil 
• 82500-57-0 ethyl 3-(2-nitrophenyl)-2-semicarbazonopropionate (E-form) 
• 82500-58-1 ethyl 3-(2-nitrophenyl)-2-semicarbazonopropionate (Z-form) 
• 5461-32-5 o-nitrophenylpyruvic acid 
• 784-98-5 ethyl 2-nitrophenylpyruvate keto tautomer 
• 95539-27-8 2-(2-carbamothioylhydrazono)-3-(2-nitrophenyl)propanoic acid 
• 95539-29-0 3-methylmercapto-6-(o-nitrobenzyl)-2,5-dihydro-1,2,4-triazin-5-one 

Downstream Products

• 82500-67-2 4-methyl-6-(2-nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine 
• 82500-66-1 2-methyl-6-(2-nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine 
• 82500-65-0 2,4-dimethyl-6-(2-nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine 
• 82500-68-3 2-acetyl-6-(2-nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine 
• 82500-70-7 5-(o-aminobenzyl)-6-azauracil 
• 95539-33-6 1-benzylideneamino-1,2-dihydroimidazo<4,5-b>quinolin-2-one 
• 95539-34-7 1-(4-nitrobenzylideneamino)-1,2-dihydroimidazo<4,5-b>quinolin-2-one 

Relevant academic research and scientific papers

SYNTHESIS OF 1,2,4-TRIAZINO- AND IMIDAZOQUINOLINE DERIVATIVES

o-Nitrophenylpyruvic acid thiosemicarbazone (I) has been cyclized to 2-thio-5-(o-nitrobenzyl)-6-azauracil (II) which has been transformed in 5-quinolin-3-one (VI).Compound VI is transformed in acid medium to 1-amino-1,2-dihydroimidazoquinolin-2-one (VIII) via the tautomer VII, and in boiling acetic acid it gives the acetylamino derivative IX.The N-amino derivative VIII reacts with carbonyl compounds to give the corresponding hydrazones X-XII, and its nitrosation gives 1,2-dihydroimidazoquinolin-2-one (XIII).

Synthesis of 6-(2-Nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine and some Derivatives

6-(2-Nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazines were prepared as intermediates fo rinvestigation aimed at the synthesis od as-triazinoquinolines.The substances were obtained by new mwthods based on the elucidation of stereochemical cond