95539-28-9

Upstream product

• 5461-32-5 o-nitrophenylpyruvic acid 
• 95539-27-8 2-(2-carbamothioylhydrazono)-3-(2-nitrophenyl)propanoic acid 

Downstream Products

• 95539-33-6 1-benzylideneamino-1,2-dihydroimidazo<4,5-b>quinolin-2-one 
• 95539-34-7 1-(4-nitrobenzylideneamino)-1,2-dihydroimidazo<4,5-b>quinolin-2-one 
• 82500-70-7 5-(o-aminobenzyl)-6-azauracil 
• 95539-29-0 3-methylmercapto-6-(o-nitrobenzyl)-2,5-dihydro-1,2,4-triazin-5-one 
• 82500-59-2 6-(2-nitrobenzyl)-3,5-dioxo-2,3,4,5-tetrahydro-as-triazine 

Relevant academic research and scientific papers

SYNTHESIS OF 1,2,4-TRIAZINO- AND IMIDAZOQUINOLINE DERIVATIVES

o-Nitrophenylpyruvic acid thiosemicarbazone (I) has been cyclized to 2-thio-5-(o-nitrobenzyl)-6-azauracil (II) which has been transformed in 5-quinolin-3-one (VI).Compound VI is transformed in acid medium to 1-amino-1,2-dihydroimidazoquinolin-2-one (VIII) via the tautomer VII, and in boiling acetic acid it gives the acetylamino derivative IX.The N-amino derivative VIII reacts with carbonyl compounds to give the corresponding hydrazones X-XII, and its nitrosation gives 1,2-dihydroimidazoquinolin-2-one (XIII).