82525-10-8

Basic information

• Product Name: Benzene, 1-chloro-4-[2-(methylthio)ethenyl]-
• CAS NO: 82525-10-8
• Molecular Formula: C9H9ClS
• Molecular Weight: 184.689
• Mol File: 82525-10-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1-chloro-4-[2-(methylthio)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-4-[2-(methylthio)ethenyl]-(82525-10-8)
• EPA Substance Registry System: Benzene, 1-chloro-4-[2-(methylthio)ethenyl]-(82525-10-8)

Safety Data

• Hazardous Substances Data: 82525-10-8(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 67-68-5 dimethyl sulfoxide 
• 23462-73-9 triphenylmethylmercapto methylenephosphorane 
• 84918-82-1 (E)-1-(p-chlorophenyl)-2-(methylsulfinyl)-2-(methylthio)ethene 

Downstream Products

• 31408-40-9 2-amino-5-(4-fluorophenyl)pyrimidine 
• 82525-22-2 5-(4-Chloro-phenyl)-2-methyl-pyrimidine 
• 82525-17-5 5-(4-chlorophenyl)pyrimidine 
• 82525-15-3 (Z)-2-(4-Chloro-phenyl)-3-methylsulfanyl-propenal 

Relevant articles and documents

The reactions of DMSO with arylaldehydes in the presence of sodium hydride

Dimethyl sulfoxide (DMSO) reacted with arylaldehydes under basic conditions to afford sulfide 1, β-(benzyloxy)styrene 2 and dialkyl sulfoxide 3, while the reaction of benzophenone with DMSO gave 1,1-diphenylethylene 4, 1,1-diphenyl-2-methylthioethylene 5 and sulfoxide 6 at the same time under the same conditions.

Stereospecific Reductive Desulfinylation of 1-Aryl-2-(methylsulfinyl)-2-(methylthio)ethenes with Grignard Reagents

(E)-1-Aryl-2-(methylsulfinyl)-2-(methylthio)ethene, obtained by the Knoevenagel-type condensation of methyl (methylthio)methyl sulfoxide with the corresponding aromatic aldehyde, was found to react with ethylmagnesium chloride to give (Z)-1-aryl-2-(methylthio)ethene predominantly.Since the reaction of (Z)-1-(methylsulfinyl)-1-(methylthio)-2-phenylethene afforded (E)-1-(methylthio)-2-phenylethene, the present reaction appeared to be stereospecific.