82568-58-9Relevant academic research and scientific papers
RING TRANSFORMATIONS OF 3-PHENYL-4-TOSYLIMINO-1,3-THIAZETIDINE-2-ONE
L'abbe, Gerrit,Dekerk, Jean-Paul,Deketele, Martine
, p. 243 - 248 (2007/10/02)
The title compound 1 can be transformed into functionalized 5- and 6-membered heterocycles by treatment with nucleophilic reagents.For instance, the reaction of 1 with tert-butyl isonitrile yields the two isomers 2 and 3, resulting from different positions of attack at the 4-membered ring.Diethylaminopropyne, on the contrary, reacts only at the C2-position of 1 giving rise to the 6-membered ring 4 in high yield.With phosphorus ylides, three pathways, all resulting from initial attack at the C2-atom of 1, have been observed depending on the substitution pattern of the ylide.
