82575-05-1

Basic information

• Product Name: (2S,3S)-3-Hydroxy-2-phenyl-butyratetetramethyl-ammonium;
• Synonyms: (2S,3S)-3-Hydroxy-2-phenyl-butyratetetramethyl-ammonium
• CAS NO: 82575-05-1
• Molecular Weight: 253.342
• Mol File: 82575-05-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-3-Hydroxy-2-phenyl-butyratetetramethyl-ammonium;(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-3-Hydroxy-2-phenyl-butyratetetramethyl-ammonium;(82575-05-1)
• EPA Substance Registry System: (2S,3S)-3-Hydroxy-2-phenyl-butyratetetramethyl-ammonium;(82575-05-1)

Safety Data

• Hazardous Substances Data: 82575-05-1(Hazardous Substances Data)

Upstream product

• 4374-66-7 rac-(2R,3R)-3-hydroxy-2-phenylbutanoic acid 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Relevant articles and documents

Dehydrative Decarboxylation of 2,3-Disubstituted 3-Hydroxycarboxylic Acids with Dimethylformamide Acetals - Mechanistic Studies and Preparative Applicability

Dimethylformamide dimethylacetal (2a) converts the threo-3-hydroxycarboxylic acids 4 smoothly into the (E)/(Z)-olefins 7/6 only if R2 is an aryl or vinyl substituent.Althougt the reaction exhibits a distinct (E)-selectivity it cannot be considered as a stereo-controlled olefin synthesis.If R2 is alkyl, 2a generates the methyl esters 10 from 4.The erythro-acids 5 react with 2a to give 43 - 95percent of >98percent sterically pure 7.As the key tranformation on the multistep way from 4/5 to 6/7 the fragmentation of the zwitterionic intermediate 11/20 is postulated.