82588-40-7

Basic information

• Product Name: 6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole
• Synonyms: 6-(4-Methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole; imidazo[2,1-b]thiazole, 2,3-dihydro-6-(4-methylphenyl)-
• CAS NO: 82588-40-7
• Molecular Formula: C₁₂H₁₂N₂S
• Molecular Weight: 216.3021
• Mol File: 82588-40-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 425.3°C at 760 mmHg
• Flash Point: 211°C
• Density: 1.27g/cm³
• Vapor Pressure: 1.93E-07mmHg at 25°C
• Refractive Index: 1.691
• CAS DataBase Reference: 6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole(82588-40-7)
• EPA Substance Registry System: 6-(4-methylphenyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole(82588-40-7)

Safety Data

• Hazardous Substances Data: 82588-40-7(Hazardous Substances Data)

Upstream product

• 1779-81-3 4,5-Dihydro-thiazol-2-ylamin 
• 619-41-0 4-(bromoacetyl)toluene 

Downstream Products

• 82588-63-4 2,3-Dihydro-5-hydroxymethyl-6-p-tolylimidazo<2,1-b>thiazole 
• 82588-45-2 2,3-Dihydro-5-formyl-6-p-tolylimidazo<2,1-b>thiazole 
• 115859-08-0 4-(6-p-Tolyl-2,3-dihydro-imidazo[2,1-b]thiazol-5-yl)-4H-pyridine-1-carboxylic acid ethyl ester 

Relevant articles and documents

Synthetic and Mechanistic Studies on the Preparation of Pyridyl-Substituted Imidazothiazoles

A new method is presented for the introduction of the 4'-pyridyl substituent into 6-aryl-2,3-dihydroimidazothiazoles.The method involves treatment of the imidazothiazolines with the reactive complex of pyridine and ethyl chloroformate and oxidative deethyl carboxylation of the dihydropyridine adducts formed.Sulfur in refluxing mesitylene was found most suitable for the latter reaction, but chromium trioxide in pyridine or KtBuO and air were also effective.