826-42-6Relevant academic research and scientific papers
Renewable waste rice husk grafted oxo-vanadium catalyst for oxidation of tertiary amines to N-oxides
Panwar, Vineeta,Bansal, Ankushi,Ray, Siddharth S.,Jain, Suman L.
, p. 71550 - 71556 (2016/08/05)
Low cost renewable waste rice husks (RH) have been used as a support for grafting of an oxo-vanadium Schiff base via covalent attachment for the oxidation of tertiary amines to N-oxide. The synthesis of the desired RH grafted oxo-vanadium complex involves prior functionalization of the RH support with amino-propyltrimethoxysilane (APTMS) followed by its reaction with salicylaldehyde to get an RH-functionalized Schiff base which subsequently reacted with vanadyl sulphate to get the targeted oxo-vanadium catalyst. The synthesized catalyst was found to be an efficient heterogeneous catalyst and afforded an excellent yield of corresponding N-oxides via oxidation of tertiary amines with hydrogen peroxide as an oxidant. Furthermore, the synthesized catalyst was found to be quite stable and showed consistent activity for five runs without any loss in activity.
Catalyst-free and selective oxidation of pyridine derivatives and tertiary amines to corresponding N-oxides with 1,2-diphenyl-1,1,2,2-tetrahydroperoxyethane
Azarifar, Davood,Mahmoudi, Boshra
, p. 645 - 651 (2016/02/19)
The catalyst-free oxidation of various pyridine derivatives and tertiary amines to their corresponding N-oxides with 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane as an efficient oxidant has been developed. The methodology proved to tolerate a number of functional groups. The reactions proceeded smoothly under solvent-free and mild conditions at room temperature. All the products were easily extracted from the reaction mixtures in excellent yields. Graphical abstract: The catalyst-free oxidation of various pyridine derivatives and tertiary amines to their corresponding N-oxides with 1,1,2,2-tetrahydroperoxy-1,2-diphenylethane as an efficient oxidant has been developed. The methodology proved to tolerate a number of functional groups. The reactions proceeded smoothly under solvent-free and mild conditions at room temperature. All the products were easily extracted from the reaction mixtures in excellent yields.
Reduction of amine N-oxides by diboron reagents
Kokatla, Hari Prasad,Thomson, Paul F.,Bae, Suyeal,Doddi, Venkata Ramana,Lakshman, Mahesh K.
experimental part, p. 7842 - 7848 (2011/12/01)
Facile reduction of alkylamino-, anilino-, and pyridyl-N-oxides can be achieved via the use of diboron reagents, predominantly bis- (pinacolato)- and in some cases bis(catecholato)diboron [(pinB)2 and (catB)2, respectively]. Reductions occur upon simply mixing the amine N oxide and the diboron reagent in a suitable solvent, at a suitable temperature. Extremely fast reductions of alkylamino- and anilino-N-oxides occur, whereas pyridyl-N-oxides undergo slower reduction. The reaction is tolerant of a variety of functionalities such as hydroxyl, thiol, and cyano groups, as well as halogens. Notably, a sensitive nucleoside N-oxide has also been reduced efficiently. The different rates with which alkylamino- and pyridyl-N-oxides are reduced has been used to perform stepwise reduction of the N,N-dioxide of (S)-(-)-nicotine. Because it was observed that (pinB)2 was unaffected by the water of hydration in amine oxides, the feasibility of using water as solvent was evaluated. These reactions also proceeded exceptionally well, giving high product yields. In constrast to the reactions with (pinB)2, triethylborane reduced alkylamino-N oxides, but pyridine N-oxide did not undergo efficient reduction even at elevated temperature. Finally, the mechanism of the reductive process by (pinB)2 has been probed by 1H and 11B NMR. (Figure presented) ; 2011 American Chemical Society.
Fe-complex of a tetraamido macrocyclic ligand: Spectroscopic characterization and catalytic oxidation studies
Sullivan, Shane Z.,Ghosh, Anindya,Biris, Alexandru S.,Pulla, Sharon,Brezden, Anna M.,Collom, Samulel L.,Woods, Ross M.,Munshi, Pradip,Schnackenberg, Laura,Pierce, Brad S.,Kannarpady, Ganesh K.
scheme or table, p. 359 - 365 (2011/01/10)
This work presents the spectroscopic characterization and reaction studies of a FeIII-complex (2) of a tetraamido macrocyclic ligand (1, 15,15-dimethyl-5,8,13,17-tetrahydro-5,8,13,17-tetraaza-dibenzo[a,g] cyclotridecene-6,7,14,16-tetraone). 2 was characterized primarily by means of EPR. In agreement with the magnetic moment (μeff = 3.87 BM), EPR spectroscopy of 2 shows signals consistent with S = 3/2 intermediate-spin ferric-iron. Besides EPR, mass spectrometry, UV/vis spectroscopy and cyclic voltammetry were used to further characterize 2. 2 is soluble in water and activates hydrogen peroxide under ambient conditions. 2 catalytically bleaches dyes, pulp and paper effluents and oxidizes several amines to their corresponding N-oxides with high turnover number and good yields.
Oxidation of organic compounds by sulfonated porous carbon and hydrogen peroxide
Shokrolahi, Arash,Zali, Abbas,Keshavarz, Mohammad Hossein
experimental part, p. 1427 - 1432 (2012/04/18)
The oxidation of organic compounds by sulfonated porous carbon and H 2O2 was studied at room temperature. Alkyl and aryl sulfides were oxidized to the corresponding sulfoxides or sulfones in excellent yields. Secondary alcohols were also converted to the corresponding esters/lactones and aldehydes to methyl esters in good yields. Moreover, aliphatic tertiary amines and substituted pyridines were oxidized to N-oxides.
Rhenium-catalyzed highly efficient oxidations of tertiary nitrogen compounds to N-oxides using sodium percarbonate as oxygen source
Jain, Suman L.,Joseph, Jomy K.,Sain, Bir
, p. 2661 - 2663 (2008/09/16)
Sodium percarbonate was found to be an ideal and efficient oxygen source for the oxidation of tertiary nitrogen compounds to N-oxides in excellent yields in presence of various rhenium-based catalysts under mild reaction conditions. Georg Thieme Verlag Stuttgart.
Silica-supported vanadium-catalyzed N-oxidation of tertiary amines with aqueous hydrogen peroxide
Rout, Laxmidhar,Punniyamurthy, Tharmalingam
, p. 1958 - 1960 (2007/10/03)
A recyclable silica supported vanadium 1 catalyzes the oxidation of tertiray amines to the corresponding N-oxides with 30% H2O 2 in high yield.
Bromamine-T/RuCl3 as an efficient system for the oxidation of tertiary amines to N-oxides
Sharma, Vishal B.,Jain, Suman L.,Sain, Bir
, p. 4281 - 4283 (2007/10/03)
A variety of tertiary amines were efficiently and selectively oxidized to the corresponding N-oxides by bromamine-T using ruthenium trichloride as catalyst in alkaline (pH8.4) acetonitrile/water (1:1) at 80°C.
Methyltrioxorhenium catalyzed aerobic oxidation of organonitrogen compounds
Sharma, Vishal B.,Jain, Suman L.,Sain, Bir
, p. 3235 - 3237 (2007/10/03)
A variety of tertiary, secondary and primary organonitrogen compounds have been efficiently and selectivity oxidized to their corresponding N-oxides, nitrones, and nitro compounds with molecular oxygen using methyltrioxorhenium as catalyst.
An unconventional cobalt-catalyzed aerobic oxidation of tertiary nitrogen compounds to N-oxides
Jain, Suman L.,Sain, Bir
, p. 1265 - 1267 (2007/10/03)
A simple system, simple workup, and excellent yields make the new method for the oxidation of tertiary nitrogen compounds described in Equation (1) an attractive, environmentally acceptable synthetic tool. Molecular oxygen serves as the oxygen source and no sacrificial agents are required.
