28405-79-0Relevant academic research and scientific papers
Inductive effects through Alkyl Groups - How long is long enough?
Tandon, Raman,Nigst, Tobias A.,Zipse, Hendrik
supporting information, p. 5423 - 5430 (2013/09/02)
The influence of the length of alkyl substituents on various kinetic, thermodynamic, and spectroscopic properties of 4-(dialkylamino)pyridines has been determined by using a combination of experimental and theoretical methods. The chain-length dependence of these properties has subsequently been analyzed by using a quantitative model for through-bond inductive effects. Substituent effects of linear alkyl groups show a saturation effect beyond four carbon atoms for numerous properties of 4-(dialkylamino)pyridines as test substrates. These observations can be rationalized by using an increment-based method for the calculation of inductive substituent effects. Copyright
Photochemical Induced Formation of α-Alkylamino or Alkylaminyl Radicals From Secondary Amines: Reaction with 4-Pyridinecarbonitrile
Caronna, Tullio,Morrocchi, Sergio
, p. 975 - 977 (2007/10/02)
The direct photolysis at 254 nm of 4-pyridinecarbonitrile in the presence of some aliphatic secondary amines brought to the substitution of the CN group and to the formation of 4-α-alkylaminopyridines, whereas the irradiation in the presence of benzophenone at 350 nm yields 4-alkylaminylpyridines and 4-diphenylketylpyridine.A mechanism is proposed to explain the different course of the reaction under the two different conditions.
