28405-79-0Relevant articles and documents
Inductive effects through Alkyl Groups - How long is long enough?
Tandon, Raman,Nigst, Tobias A.,Zipse, Hendrik
supporting information, p. 5423 - 5430 (2013/09/02)
The influence of the length of alkyl substituents on various kinetic, thermodynamic, and spectroscopic properties of 4-(dialkylamino)pyridines has been determined by using a combination of experimental and theoretical methods. The chain-length dependence of these properties has subsequently been analyzed by using a quantitative model for through-bond inductive effects. Substituent effects of linear alkyl groups show a saturation effect beyond four carbon atoms for numerous properties of 4-(dialkylamino)pyridines as test substrates. These observations can be rationalized by using an increment-based method for the calculation of inductive substituent effects. Copyright