826-60-8Relevant academic research and scientific papers
Platinum-Catalyzed Intramolecular Hydrosilation of Allylamines: Formation of 1-Aza-2-silacyclobutanes and Application to Stereoselective Synthesis of 2-Amino Alcohols
Tamao, Kohei,Nakagawa, Yoshiki,Ito, Yoshihiko
, p. 3438 - 3439 (2007/10/02)
N,N-Bis(dimethylsilyl)allylamines undergo intramolecular hydrosilation in the presence of Pt2O>2 (0.2 mol percent) to form four-membered cyclic compounds, 1-aza-2-silacyclobutane derivatives, which can be transformed into 2-amino alcohols by oxidation with 30percent H2O2 in the presence of KF and KHCO3.
A New Synthesis of 2-Aminoalcohols from O-Trimethylsilylated Cyanohydrins
Krepski, Larry R.,Jensen, Karen M.,Heilmann, Steven M.,Rasmussen, Jerald K.
, p. 301 - 303 (2007/10/02)
The reaction of O-trimethylsilylated cyanohydrins with Grignard reagents, followed by reduction, represents a convenient synthesis of 2-aminoalcohols.
