82619-72-5Relevant academic research and scientific papers
Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-assisted Atwal reaction as potential anticancer agents
Antoniazi, Mariana K.,Filho, Eclair Venturini,Greco, Sandro J.,Loureiro, Laiza B.,Pessoa, Claudia,Pina, Jorge W. S.,Pinheiro, Carlos B.,Ribeiro, Marcos A.,Taranto, Alex G.,Guimar?es, Celina J.,de Oliveira, Fátima C. E.
supporting information, (2021/07/13)
A simple and fast methodology under microwave irradiation for the synthesis of 2-aminopyrimidine and pyrazole derivatives using Atwal reaction is reported. After the optimization of the reaction conditions, eight 2-aminolpyrimidines containing ferrocene a
Pyrrole–aminopyrimidine ensembles: Cycloaddition of guanidine to acylethynylpyrroles
Budaev, Arsalan B.,Ivanov, Andrey V.,Petrova, Olga V.,Sagitova, Elena F.,Sobenina, Lyubov N.,Trofimov, Boris A.,Ushakov, Igor A.
, (2021/06/16)
An efficient method for the synthesis of pharmaceutically prospective pyrrole–aminopyrimidine ensembles (in up to 91% yield) by the cyclocondensation of easily available acylethynylpyrroles with guanidine nitrate has been developed. The reaction proceeds
