82633-79-2

Basic information

• Product Name: 2-methyl-4,5-trimethylene-4-isothiazolin-3-one
• Synonyms: 2-methyl-4,5-trimethylene-4-isothiazolin-3-one;2H-Cyclopentdisothiazol-3(4H)-one, 5,6-dihydro-2-methyl-;PROMEXALX50PRESERVATIVE;5,6-dihydro-2-methyl-2H-Cyclopent[d]isothiazol-3(4H)-one;2,3,5,6-tetrahydro-2-methyl-2H-cyclopenta[d]-1,2-thiazol-3-one;2-Methyl-5,6-dihydro-4H- cyclopenta[d]isothiazol-3(2H)-one;2-methyl-5,6-dihydro-2H-cyclopenta[d]isothiazol-3(4H)-one
• CAS NO: 82633-79-2
• Molecular Formula: C7H9NOS
• Molecular Weight: 155.21746
• EINECS: 407-630-9
• Mol File: 82633-79-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 268.7°Cat760mmHg
• Flash Point: 116.3°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 0.00758mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 2-methyl-4,5-trimethylene-4-isothiazolin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4,5-trimethylene-4-isothiazolin-3-one(82633-79-2)
• EPA Substance Registry System: 2-methyl-4,5-trimethylene-4-isothiazolin-3-one(82633-79-2)

Safety Data

• Hazard Codes: T,N
• Statements: 25-41-43-50/53
• Safety Statements: 22-26-36/37/39-45-60-61
• Hazardous Substances Data: 82633-79-2(Hazardous Substances Data)

Usage

Description

2-Methyl-4,5-trimethylene-4-isothiazolin-3-one (MTI) is a biocide which induced contact dermatitis in a laboratory technician also sensitive to BIT.

Contact allergens

This biocide induced contact dermatitis in a laboratory technician, also sensitive to the other isothiazolinone BIT.

InChI:InChI=1/C7H9NOS/c1-8-7(9)5-3-2-4-6(5)10-8/h2-4H2,1H3

Upstream product

• 82634-76-2 2-oxo-cyclopentanecarboxylic acid methylamide 
• 79-03-8 propionyl chloride 

Relevant articles and documents

Synergistic biocide composition

A biocide composition is provided as an addition to substances that can be infected by harmful microorganisms, in which the biocide composition has at least two active biocidal substances, one of which is 2-methylisothiazolin-3-one. The composition is characterized in that it contains 1,2-benzisothiazolin-3-one, compositions containing 5-chloro-2-methylisothiazolin-3-one being excluded. In comparison with its individual components, the composition of the invention has a synergistic biocidal activity.

Sulfur containing diamides and antimicrobial use

A compound of the formula STR1 in which R1 and R2 taken together, and R3 and R4 taken together, independently represent a polymethylene chain having 3 or 4 carbon atoms, or a polymethylene chain having 3 or 4 carbon atoms substituted by at least one lower alkyl radical having from 1 to 4 carbon atoms, and R5 to R8 are independently hydrogen, hydrocarbyl or substituted hydrocarbyl. Typically R1 and R2 and also R3 and R4 complete a trimethylene ring, R5 and R7 are each hydrogen and R6 and R8 are alkyl such as methyl. The compounds have microbiological activity.