82635-69-6

Basic information

• Product Name: N-(2-chloro-5-methylphenyl)-S-methylisothiourea
• CAS NO: 82635-69-6
• Molecular Weight: 214.719
• Mol File: 82635-69-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chloro-5-methylphenyl)-S-methylisothiourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloro-5-methylphenyl)-S-methylisothiourea(82635-69-6)
• EPA Substance Registry System: N-(2-chloro-5-methylphenyl)-S-methylisothiourea(82635-69-6)

Safety Data

• Hazardous Substances Data: 82635-69-6(Hazardous Substances Data)

Upstream product

• 95-79-4 5-chloro-2-methyl-benzenamine 
• 72806-61-2 1-(5-Chloro-2-methylphenyl)-2-thiourea 
• 74-88-4 methyl iodide 

Downstream Products

• 82635-94-7 2-[3-(5-Chloro-2-methyl-phenyl)-2-methyl-isothioureidomethylene]-malonic acid diethyl ester 
• 82636-22-4 1-(5-Chloro-2-methyl-phenyl)-2-methylsulfanyl-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 89069-30-7 3-(5-chloro-2-methylphenyl)-2-methylthio-4(3H)-pyrimidinone 

Relevant articles and documents

Synthesis & Pharmacological Evaluation of Ethyl 3-Substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates

A number of ethyl 3-substituted-phenyl-2-methylmercapto/ phenyl/ methyl-4(3H)-pyrimidone-5-carboxylates (V) have been prepared by the reaction of amidines (III) with diethyl ethoxymethylenemalonate.In order to confirm the structure (V), ethyl 3-(2'-methylphenyl)-2-methylmercapto-4(3H)pyrimidone-5-carboxylate (103) has been transformed into the earlier synthesised 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone (115) by decarboxylation of 3-(2'-methylphenyl)-2-methylmercapto-4(3H)-pyrimidone-5-carboxylic acid (114), obtained by the alkaline hydrolysis of 103.Someof these compounds have shown antiinflammatory, diuretic and antipassive cutaneous anaphylaxis activities.