82658-22-8

Upstream product

• 121442-68-0 8-[(Z)-2-(6,7-Dimethoxy-1,4-bis-methoxymethoxy-9-oxo-9H-xanthen-3-yl)-vinyl]-6-hydroxy-10a-methyl-2,3,10,10a-tetrahydro-oxazolo[3,2-b]isoquinolin-5-one 
• 20389-01-9 2,6-diiodo-p-benzoquinone 
• 490-64-2 asaronic acid 
• 137789-86-7 7-Bromo-4-hydroxy-5,8-dimethoxy-2-methyl-phenanthrene-3-carboxylic acid ethyl ester 
• 137787-57-6 (+/-)-cervinomycin A₁-trimethylether 
• 137787-68-9 3-acetylmethyl-1,7,10,11,14-pentamethoxynaphtho<1,2-b>xanthone-2-carboxylic acid methyl ester 
• 137789-91-4 8,11,12,15,16-Pentamethoxy-3-methyl-3,4-dihydro-2,9-dioxa-hexaphene-1,14-dione 
• 137789-90-3 4,5-Dimethoxy-2-(12-methoxy-9-methyl-1,4,11-trioxo-1,8,9,11-tetrahydro-4H-10-oxa-benzo[a]anthracen-3-yloxy)-benzoic acid methyl ester 
• 137789-87-8 7-Bromo-4,5,8-trimethoxy-2-(2-oxo-propyl)-phenanthrene-3-carboxylic acid ethyl ester 
• 137789-88-9 3-Bromo-1,4,12-trimethoxy-9-methyl-8,9-dihydro-10-oxa-benzo[a]anthracen-11-one 
• 137789-83-4 4-(6-Bromo-5,8-dimethoxy-naphthalen-2-yl)-3-methyl-butyric acid ethyl ester 
• 137789-84-5 4-(6-Bromo-5,8-dimethoxy-naphthalen-2-yl)-3-methyl-butyric acid 
• 137789-85-6 7-Bromo-5,8-dimethoxy-2-methyl-2,3-dihydro-1H-phenanthren-4-one 
• 20029-76-9 methyl 2,4,5-trimethoxybenzoate 

Downstream Products

• 82658-23-9 Cervinomycin A₁ 
• 5722-93-0 2-hydroxy-4,5-dimethoxybenzoic acid 

Relevant academic research and scientific papers

167-A, a new antibiotic produced by a mutant of an inactive wild strain of Amycolata autotrophica

Two related antibiotics, 167-A and 167-B, were isolated from the fermentation broth of a mutant of an inactive wild strain of Amycolata autotrophica. Antibiotic 167-B was found to be cervinomycin A2; antibiotic 167-A is a new representative of the same group and has the structure of 18-O-demethyl cervinomycin A2.

Total syntheses of (±) cervinomycins A1 and A2

Regiocontrolled total syntheses of cervinomycins A1 (1) and A2 (2_have been achieved from easily accessible 6-acetyl-2-bromo-1,4,-dimethoxynaphthalene (4).