82660-87-5

Basic information

• Product Name: GLYCYL-D-SERINE
• Synonyms: H-GLY-D-SER-OH;GLYCYL-D-SERINE;gly-D-ser;D-Serine, glycyl- (9CI);(R)-2-Glycylamino-3-hydroxypropionic acid;Gly-D-Ser-OH;N-Glycyl-D-serine;NSC 523194
• CAS NO: 82660-87-5
• Molecular Formula: C5H10N2O4
• Molecular Weight: 162.14
• Product Categories: GLYCINESCAFFOLD;Biochemistry;Oligopeptides;Peptide Synthesis
• Mol File: 82660-87-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 513 °C at 760 mmHg
• Flash Point: 264.1 °C
• Appearance: /
• Density: 1.432 g/cm³
• Vapor Pressure: 1.14E-12mmHg at 25°C
• Refractive Index: 9 ° (C=2, H2O)
• Storage Temp.: ?20°C
• PKA: 2.97±0.10(Predicted)
• CAS DataBase Reference: GLYCYL-D-SERINE(CAS DataBase Reference)
• NIST Chemistry Reference: GLYCYL-D-SERINE(82660-87-5)
• EPA Substance Registry System: GLYCYL-D-SERINE(82660-87-5)

Safety Data

• Hazardous Substances Data: 82660-87-5(Hazardous Substances Data)

Usage

General Description

GLYCYL-D-SERINE is a dipeptide composed of glycine and D-serine. It is a non-proteinogenic amino acid derivative that is involved in mediating and modulating various physiological processes in the body, including neurotransmission and neurotransmitter release. GLYCYL-D-SERINE has been found to exhibit neuroprotective properties and has been studied for its potential in the treatment of neurological disorders and brain injuries. It is also being investigated for its role in cognitive function and memory enhancement. Additionally, GLYCYL-D-SERINE has shown promise in promoting wound healing and tissue repair. Overall, this chemical compound has demonstrated potential therapeutic applications and continues to be the subject of research in various fields of medicine and biotechnology.

InChI:InChI=1/C5H10N2O4/c6-1-4(9)7-3(2-8)5(10)11/h3,8H,1-2,6H2,(H,7,9)(H,10,11)/t3-/m1/s1

Upstream product

• 67206-28-4 N-chloroacetyl-DL-serine 
• 91841-16-6 N-(N,N-phthaloyl-glycyl)-DL-serine 
• 3062-02-0 O-benzyl-N-chloroacetyl-DL-serine 
• 109591-99-3 N-benzyloxycarbonylglycyl-DL-serine 
• 3062-03-1 O-benzyl-N-glycyl-DL-serine 
• 108849-83-8 benzyloxycarbonyl-Gly-Ser-OMe 

Downstream Products

• 89886-21-5 O-glycyl-DL-serine 
• 1738-97-2 H-Gly-Ser-OBzl 
• 95767-06-9 N-hippuroyl-L-serine 

Relevant articles and documents

Thermodynamic characteristics of protolytic equilibria in aqueous solutions of glycyl peptides

Protolytic equilibria in aqueous solutions of glycyl-DL-serine, glycyl-DL-threonine, and glycyl-DL-valine are investigated by means of potentiometry and calorimetry. Dissociation constants and heat effects of the above dipeptides are determined. Standard

Disulfide bridged cyclic peptides containing a cgridri sequence useful in control of hypertension

Disulfide bridged cyclic peptides are described which are preferably 13 to 20 amino acid residues in length and which include the endocyclic sequence cys-gly-arg-ile-asp-arg-ile. Peptides of this class are selective for and show picomolar-range affinity for the non-guanyl cyclase-coupled atrial peptide receptor. Affinity for this receptor is associated with potentiation of the mean arterial pressure response to atrial peptide and these peptides are therefore useful in control of hypertension. Peptides of most interest are of the formula wherein X1 is the peptidic fragment ser-ser; wherein X2 is a peptidic fragment selected from gly-ser-gly-leu, gly-ala-gly-leu and gly-leu; wherein X3 is the peptidic fragment asn-ser-phe-arg; wherein m is zero or one, n is one and r is one; and wherein A represents an amino terminus or its pharmaceutically--acceptable salt, and B represents a carboxyl terminus or its pharmaceutically-acceptable ester, amide or salt.