82672-31-9Relevant academic research and scientific papers
Ln[N(SiMe3)2]3-Catalyzed Cross-Diinsertion of C≡N/C≡C into an N-H Bond: Facile Synthesis of 1,2,4-Trisubstituted Imidazoles from Propargylamines and Nitriles
Hong, Longcheng,Shao, Yinlin,Zhang, Lixin,Zhou, Xigeng
, p. 8551 - 8555 (2014)
A lanthanide-catalyzed sequential insertion of C≡N and C≡C into an N-H bond is presented. The convenient reaction, which proceeds under mild conditions, is an efficient method for preparing 1,2,4-trisubstituted imidazoles directly from readily available propargylamines and nitriles.
Unusual 1,4-methylene transfer from a Simmons-Smith reagent to 1,3- diazabuta-1,3-dienes
Jayakumar,Ishar,Mahajan, Mohinder P.
, p. 6557 - 6560 (1998)
Novel 1,4 methylene transfer from a Simmons-Smith reagent to 1-aryl-4- secondary amino-4-methylthio or methyl-2-phenyl-1,3-diazabuta-1,3-dienes leading to 1-aryl-2-phenyl-4-secondary amino or methyl-imidazoles are described.
Cu(II)-mediated aminooxygenation of alkenylimines and alkenylamidines with TEMPO
Sanjaya, Stephen,Chua, Sze Hui,Chiba, Shunsuke
, p. 1657 - 1661 (2012/07/17)
A method for the synthesis of oxymethyl dihydropyrroles (pyrrolines) and dihydroimidazoles has been developed via Cu(II)-mediated intramolecular aminooxygenation of alkenylimines and alkenylamidines, respectively, with 2,2,6,6-tetramethyl-1-piperidinyloxy radical (TEMPO). Georg Thieme Verlag Stuttgart · New York.
Synthesis, structure-activity relationships at the GABAA receptor in rat brain, and differential electrophysiological profile at the recombinant human GABAA receptor of a series of substituted 1,2-diphenylimidazoles
Asproni, Battistina,Talani, Giuseppe,Busonero, Fabio,Pau, Amedeo,Sanna, Sebastiano,Cerri, Riccardo,Mascia, Maria Paola,Sanna, Enrico,Biggio, Giovanni
, p. 2638 - 2645 (2007/10/03)
A series of new 1,2-diphenylimidazole derivatives (1a-x) were synthesized and evaluated for their ability to potentiate γ-aminobutyric acid (GABA)-evoked currents in Xenopus laevis oocytes expressing recombinant human GABAA receptors. Many of t
Studies on Azole Compounds. VI. Reactions of 2,4- and 2,5-Disubstituted Thiazole N-Oxides with Aryl Isocyanates
Honjo, Noriko,Niiya, Tokihiro,Goto, Yoshinobu
, p. 1722 - 1730 (2007/10/02)
The reactions of 2,4- (Ia-d) and 2,5-disubstituted thiazole 3-oxides (Ie-f) with aryl isocyanates (II) were studied.While the reactions of Ia-d with II proceeded smoothly to give bis(5-imidazolyl) disulfides (IV), those of Ie-f with II did not take place.
