82679-65-0Relevant academic research and scientific papers
N-Unsubstituted β-Lactams from β-Hydroxy-α-amino Acids. Facile Preparation of Intermediates for Isocephalosporins
Bose, Ajay K.,Manhas, M. S.,Vincent, J. E.,Gala, K.,Fernandez, I. F.
, p. 4075 - 4081 (2007/10/02)
A facile method has been devised for the synthesis of N-unsubstituted β-lactams.The cis-azido β-lactam (13) obtained by the reaction of azidoacetyl chloride and the Schiff base (10), derived from cinnamaldehyde and a threonine ester, is subjected to contr
Methods and intermediates for preparing cis-4-oxoazetidine intermediates
-
, (2008/06/13)
The stereospecific cycloaddition of nitrogen containing acetic acid halides or anhydrides with Schiff bases having a carbalkoxy group substituted on the methine carbon atom offers new intermediates and methods for preparing synthetic cephalosporin congeners having antibacterial activity.
8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives
-
, (2008/06/13)
Novel bicyclic β-lactams and intermediates useful in their preparation are disclosed. In particular, 7β-acyl-amino- and 7β-amino-8-oxo-4-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acids are prepared. The acylated compounds are antibacterial agents.
