826994-47-2Relevant academic research and scientific papers
Alkynyltrifluoroborates as versatile tools in organic synthesis: A new route to spiroketals
Doubsky, Jan,Streinz, Ludvik,Saman, David,Zednik, Jiri,Koutek, Bohumir
, p. 4909 - 4911 (2007/10/03)
(Chemical Equation Presented) A simple and efficient two-step approach to spiroketals is described. Key steps include the preparation of functionalized hydroxyl α-alkynones by ring-opening reactions of lactones with lithium alkynyltrifluoroborates followed by a palladium-catalyzed hydrogenation/ spirocyclization of the prespiroketal intermediate.
