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4-bromo-5-chloro-2-nitrophenylamine is an aromatic amine with the molecular formula C6H4BrClN2O2, featuring a nitro group and halogen substituents. It is a yellow to brown crystalline solid that is moderately soluble in organic solvents and has a melting point of approximately 140-145°C. 4-bromo-5-chloro-2-nitrophenylamine is recognized for its wide application in the pharmaceutical industry as a building block for synthesizing various drugs and pharmacologically active compounds, as well as its use as an intermediate in the production of dyes and agricultural chemicals.

827-33-8

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827-33-8 Usage

Uses

Used in Pharmaceutical Industry:
4-bromo-5-chloro-2-nitrophenylamine is used as a building block for the synthesis of various drugs and pharmacologically active compounds due to its unique chemical structure and reactivity.
Used in Dye Production:
4-bromo-5-chloro-2-nitrophenylamine is used as an intermediate in the production of dyes, contributing to the development of new colorants with specific properties.
Used in Agricultural Chemicals:
4-bromo-5-chloro-2-nitrophenylamine is utilized as an intermediate in the production of agricultural chemicals, potentially enhancing the effectiveness of these products.
Safety Precautions:
It is crucial to handle and store 4-bromo-5-chloro-2-nitrophenylamine with proper safety measures, as it may be harmful if ingested, inhaled, or comes into contact with the skin.

Check Digit Verification of cas no

The CAS Registry Mumber 827-33-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,2 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 827-33:
(5*8)+(4*2)+(3*7)+(2*3)+(1*3)=78
78 % 10 = 8
So 827-33-8 is a valid CAS Registry Number.

827-33-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromo-5-chloro-2-nitroaniline

1.2 Other means of identification

Product number -
Other names 4-bromo-5-chloro-2-nitroaniline

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:827-33-8 SDS

827-33-8Relevant academic research and scientific papers

PYRAZOLES AS MODULATORS OF HEMOGLOBIN

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Page/Page column 140; 141, (2020/06/19)

The invention relates to pyrazole derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to HbS modulators of formula

HETEROARYL RHEB INHIBITORS AND USES THEREOF

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Paragraph 00669, (2018/11/10)

The present invention provides compounds, compositions thereof, and methods of using the same. Compositions comprising a compound of this invention or a pharmaceutically acceptable derivative thereof and a pharmaceutically acceptable carrier, adjuvant, or vehicle. The amount of the compound in compositions of this invention is such that it is effective to measurably inhibit Rheb, in a biological sample or in a patient.

HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

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Paragraph 0143-0146, (2018/07/28)

The present specification relates to a heterocyclic compound represented by chemical formula 1 and an organic light emitting device comprising the same. The heterocyclic compound may be used as a material of an organic material layer of an organic light e

HETEROCYCLIC COMPOUNDS AND USE THEREOF AS MODULATORS OF TYPE III RECEPTOR TYROSINE KINASES

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Paragraph 1021, (2016/08/03)

Provided herein are heterocyclic compounds for treatment of CSF1R, FLT3, KIT, and/or PDGFRβ kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.

SERINE/THREONINE PAK1 INHIBITORS

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Page/Page column 161-162, (2013/03/26)

Compounds having the formula I wherein A, Z, R1a, R1b, R2, R3, R4, R5, R6, R7, R9, R10, Ra, Rb and n are as defined herein are inhibitors of PAK1. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.

SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF

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Page/Page column 78-79, (2010/04/03)

The present application relates to novel substituted 5-aminopyrazoles, methods of production thereof, use thereof alone or in combinations for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases.

Benzimidazole Modulators of VR1

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Page/Page column 176, (2008/06/13)

The invention is directed to compounds of Formula (I): to pharmaceutical compositions containing such compounds and to methods of treatment using them.

Crystal packing: An examination of the packing of molecules approximately isosteric with 4,5-dichlorophthalic anhydride

Britton, Doyle,Noland, Wayland E.,Pinnow, Matthew J.,Young Jr., Victor G.

, p. 1175 - 1192 (2007/10/03)

The crystal structures of five 5,6-disubstituted benzofurazan 1-oxides are presented and compared with five previously reported structures: three polymorphs of 5,6-dichlorobenzofurazan 1-oxide plus 4,5-dichloro- and 4,5-dibromophthalic anhydride. All but one of these compounds pack with similar two-dimensional layers. The benzofurazan oxides all show disorder about a crystallographic twofold or pseudo-twofold axis. In addition, six complexes of phthalic anhydride and benzofurazan oxides are reported. With the packing in the complexes principally directed by the π complexing, the disorder, invariably found in the uncomplexed benzofurazan oxides, is diminished, and, in two cases, eliminated.

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