82722-95-0

Upstream product

• 51245-61-5 5-acetylamino-2,6-dimethyl-3H-pyrimidin-4-one 
• 141-52-6 sodium ethanolate 
• 5431-93-6 ethyl 2-(acetylamino)-3-oxobutanoate 
• 51245-61-5 5-acetylamino-2,6-dimethyl-3H-pyrimidin-4-one 
• 1268511-80-3 ethyl 3-acetimidamido-5-methyl-1H-pyrrole-2-carboxylate hydrochloride 
• 1005326-26-0 ethyl 3-amino-5-methyl-1H-pyrrole-2-carboxylate 

Downstream Products

• 41040-24-8 4-chloro-2,6-dimethyl-5H-pyrrolo[3,2-d]pyrimidine 
• 1268511-81-4 7-Bromo-4-chloro-2,6-dimethyl-5H-pyrrolo[3,2-d]pyrimidine 

Relevant academic research and scientific papers

INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF

The present invention relates to novel compounds which are capable of inhibiting certain amine oxidase enzymes. These compounds are useful for treatment of a variety of indications, e.g., fibrosis, cancer and/or angiogenesis in human subjects as well as i

PYRROLO[3,2] PYRIMIDINE DERIVATIVES AS INDUCERS OF HUMAN INTERFERON

Compounds of formula (I) and salts thereof: (I) wherein R1 is hydrogen, methyl or –(CH2 )2 OR3, R2 is methyl or –(CH2)2 OR4, or R1 and R2, together with the nitrogen atom to which they are attached, are linked to form a 5-or 6- membered heterocyclyl wherein the 6-membered heterocyclyl is optionally substituted by two hydroxy substituents; R3 and R4 are each independently hydrogen or methyl; and n is an integer having a value of 5 or 6, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment or prevention of various disorders, for example the treatment or prevention of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants.

METHYLPYRROLOPYRIMIDINECARBOXAMIDES

The compounds of Formula (I), wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiesterase.

METHYLPYRROLOPYRIMIDINECARBOXAMIDES

The compounds of formula (I) wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, and the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiestera

Compounds and methods which modulate feeding behavior and related diseases

There are provided compounds, compositions and methods of use thereof in the modulation of feeding behavior, obesity, diabetes, cancer (tumor), inflammatory disorders, depression, stress related disorders, Alzheimer's disease and other disease conditions.