827348-36-7Relevant academic research and scientific papers
Linear β-amino alcohol catalyst anchored on functionalized magnetite nanoparticles for enantioselective addition of dialkylzinc to aromatic aldehydes
Ciprioti, Stefano Vecchio,De Angelis, Martina,Di Pietro, Federica,Iannoni, Marika,Pilloni, Luciano,Primitivo, Ludovica,Ricelli, Alessandra,Righi, Francesco,Righi, Giuliana,Sappino, Carla,Suber, Lorenza
, p. 29688 - 29695 (2020/10/26)
A linear β-amino alcohol ligand, previously found to be a very efficient catalyst for enantioselective addition of dialkylzinc to aromatic aldehydes, has been anchored on differently functionalized superparamagnetic core-shell magnetite-silica nanoparticles (1a and 1b). Its catalytic activity in the addition of dialkylzinc to aldehydes has been evaluated, leading to promising results, especially in the case of 1b for which the recovery by simple magnetic decantation and reuse was successfully verified. This journal is
Chiral phosphoric acid catalyzed asymmetric transfer hydrogenation of bulky aryl ketones with ammonia borane
Zhou, Qiwen,Meng, Wei,Feng, Xiangqing,Du, Haifeng,Yang, Jing
supporting information, (2019/11/28)
An asymmetric transfer hydrogenation of bulky aryl ketones with ammonia borane was successfully realized with chiral phosphoric acid (CPA) as catalyst and water as additive. A variety of optically active secondary alcohols were obtained in good to high yi
A Highly Active Manganese Catalyst for Enantioselective Ketone and Ester Hydrogenation
Widegren, Magnus B.,Harkness, Gavin J.,Slawin, Alexandra M. Z.,Cordes, David B.,Clarke, Matthew L.
supporting information, p. 5825 - 5828 (2017/05/12)
A new hydrogenation catalyst based on a manganese complex of a chiral P,N,N ligand has been found to be especially active for the hydrogenation of esters down to 0.1 mol % catalyst loading, and gives up to 97 % ee in the hydrogenation of pro-chiral deactivated ketones at 30–50 °C.
Application of well-defined chain-end-functionalized polystyrenes with dendritic chiral ephedrine moieties as reagents for highly catalytic enantioselective addition of dialkylzincs to aldehydes
El-Shehawy, Ashraf A.,Sugiyama, Kenji,Hirao, Akira
, p. 425 - 434 (2008/09/19)
A series of well-defined chain-end-functionalized polystyrenes having a definite number of chiral ephedrine moieties dendritically distributed at the periphery of their hyperbranched chain-ends were evaluated as chiral catalysts for the enantioselective addition of dialkylzinc reagents to aldehydes. These dendritic macromolecules worked well as homogeneous chiral catalysts and exhibited high catalytic activity and enantioselectivity very similar to those observed for the corresponding monomeric chiral catalysts. The optimum amount of chiral catalyst was found to be 5 mol %. A profound number effect of the chiral ephedrine moieties was observed, and PS(Ephed)8 having eight chiral ephedrine moieties at the periphery was found to be superior to other dendritic chiral catalysts. The enantioselectivity reached a value of 95% in the addition of diisopropylzinc to 3-phenylpropanal. The dendritic chiral catalysts could be easily recovered from the reaction solution by using a solvent precipitation method, and the recovered catalyst showed no significant loss of its catalytic activity or enantioselectivity.
