827349-65-5Relevant articles and documents
Solution-phase parallel synthesis of new 2H-pyrimido-[4,5-e][1,2,4]triazin- 3-ylidenecyanamides
Lee, Ill Young,Kim, Sang Yo,Lee, Jin Young,Yu, Chan-Mo,Lee, Duck Hyung,Gong, Young-Dae
, p. 9319 - 9322 (2007/10/03)
A practical synthesis of 2H-pyrimido[4,5-e][1,2,4]triazin-3- ylidenecyanamides has been developed. The key step is the coupling reaction of an aryldiazonium salt with 1-cyano-3-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4- ylamino)-2-methylisothiourea followed by intramolecular cyclization. A library of 2H-pyrimido[4,5-e][1,2,4]triazin-3-ylidenecyanamides was prepared in two steps from 6-aminouracils using this method.