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82787-74-4

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82787-74-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 82787-74-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,7,8 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82787-74:
(7*8)+(6*2)+(5*7)+(4*8)+(3*7)+(2*7)+(1*4)=174
174 % 10 = 4
So 82787-74-4 is a valid CAS Registry Number.

82787-74-4Relevant articles and documents

Benzofused hydroxamic acids: Useful fragments for the preparation of histone deacetylase inhibitors. Part 1: Hit identification

Marastoni, Elena,Bartoli, Sandra,Berettoni, Marco,Cipollone, Amalia,Ettorre, Alessandro,Fincham, Christopher I.,Mauro, Sandro,Paris, Marielle,Porcelloni, Marina,Bigioni, Mario,Binaschi, Monica,Nardelli, Federica,Parlani, Massimo,Maggi, Carlo A.,Fattori, Daniela

, p. 4091 - 4095 (2013)

In the search for a new class of histone deacetylase inhibitors, we prepared a series of simple benzofused hydroxamic acids to find an anchoring fragment of minimal molecular weight. These initial hits, all belonging to the benzothiophene class, showed very good ligand efficiencies. Following these findings, a classical fragment growing approach was performed to increase binding affinity and cytotoxicity.

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