82822-28-4

Basic information

• Product Name: 1,2-Benzenediol, 4-methoxy-, diacetate
• CAS NO: 82822-28-4
• Molecular Formula: C11H12O5
• Molecular Weight: 224.213
• Mol File: 82822-28-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol, 4-methoxy-, diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol, 4-methoxy-, diacetate(82822-28-4)
• EPA Substance Registry System: 1,2-Benzenediol, 4-methoxy-, diacetate(82822-28-4)

Safety Data

• Hazardous Substances Data: 82822-28-4(Hazardous Substances Data)

Upstream product

• 69818-23-1 4-methoxy-[1,2]benzoquinone 
• 108-24-7 acetic anhydride 
• 150-76-5 4-methoxy-phenol 
• 1315577-29-7 C₁₅H₂₆O₃Si 
• 1200-06-2 4-methoxyphenyl acetate 
• 1185-59-7 tetraethylammonium acetate 
• 3934-97-2 4-methoxycatechol 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 150-19-6 O-methylresorcine 

Relevant articles and documents

Synthesis of catechols from phenols via Pd-catalyzed silanol-directed C-H oxygenation

A silanol-directed, Pd-catalyzed C-H oxygenation of phenols into catechols is presented. This method is highly site selective and general, as it allows for oxygenation of not only electron-neutral but also electron-poor phenols. This method operates via a silanol-directed acetoxylation, followed by a subsequent acid-catalyzed cyclization reaction into a cyclic silicon-protected catechol. A routine desilylation of the silacyle with TBAF uncovers the catechol product.

Efficient ortho-oxidation of phenols with diacyl peroxides

A stable symmetric diacyl peroxide, m-chlorobenzoyl peroxide (mCBPO), and an asymmetric diacyl peroxide, chloroacetyl m-chlorobenzoyl peroxide (CAMCBPO), were synthesized from m-chloroperbenzoic acid. Both peroxides oxidized phenols selectively at the ortho position predoninantly. CAMCBPO gave para-oxidized compounds as minor products from some phenols. The improvement of the yield of ortho-oxidation of phenols with mCBPO was also reported.