3934-97-2

Basic information

• Product Name: 4-METHOXYCATECHOL
• Synonyms: 4-METHOXYCATECHOL;4-Methoxyactechol;4-Methoxybenzene-1,2-diol;1,2-Benzenediol, 4-Methoxy-
• CAS NO: 3934-97-2
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.14
• Mol File: 3934-97-2.mol
• Article Data: 25

Chemical Properties

• Melting Point: 48-50 °C
• Boiling Point: 307.6°Cat760mmHg
• Flash Point: 139.8°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 0.000395mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 9.42±0.10(Predicted)
• CAS DataBase Reference: 4-METHOXYCATECHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXYCATECHOL(3934-97-2)
• EPA Substance Registry System: 4-METHOXYCATECHOL(3934-97-2)

Safety Data

• Hazardous Substances Data: 3934-97-2(Hazardous Substances Data)

Usage

General Description

4-Methoxycatechol is a chemical compound with the molecular formula C8H10O3. It is a derivative of catechol, a phenolic compound commonly found in plants. 4-Methoxycatechol is used in organic synthesis as a precursor to various pharmaceutical drugs and agricultural chemicals. It is also used in the production of polymer resins and as a stabilizer for natural and synthetic polymers. Additionally, 4-Methoxycatechol has antioxidant properties and is used in the manufacturing of personal care products and cosmetics. 4-METHOXYCATECHOL has a variety of industrial and commercial applications due to its unique chemical properties.

InChI:InChI=1/C7H8O3/c1-10-5-2-3-6(8)7(9)4-5/h2-4,8-9H,1H3

Upstream product

• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 88755-15-1 1,2-dibenzyloxy-4-methoxybenzene 
• 150-76-5 4-methoxy-phenol 
• 150-19-6 O-methylresorcine 
• 10365-98-7 3-methoxyphenylboronic acid 
• 96-96-8 4-methoxy-2-nitroaniline 
• 108-24-7 acetic anhydride 
• 167683-93-4 2-fluoro-4-methoxy-phenol 
• 60264-88-2 C₇H₈O₂*C₆H₁₅N 
• 1122-95-8 sodium 4-methoxyphenolate 
• 1315577-29-7 C₁₅H₂₆O₃Si 
• 99358-29-9 2-acetoxy-4-methoxy-1-nitro-benzene 
• 704-14-3 3-methoxy-6-nitro-phenol 
• 139-85-5 3,4-dihydroxybenzaldehyde 

Downstream Products

• 88755-15-1 1,2-dibenzyloxy-4-methoxybenzene 
• 137669-06-8 2-hydroxy-5-(tosyloxy)anisole 
• 137669-07-9 3-hydroxy-4-(tosyloxy)anisole 
• 137669-15-9 3-methoxy-4-(tosyloxy)anisole 
• 82822-28-4 2-(acetoxy)-5-methoxyphenyl acetate 
• 5676-57-3 5-Methoxy-2-methyl-benzoxazole 
• 1448465-03-9 5-(4,5-dihydroxy-2-methoxyphenyl)-2,2-dimethyl[1,3]dioxane-4,6-dione 
• 1025708-69-3 5-methoxy-2-phenyl-benzo[1,3]dioxole 
• 1702-67-6 2,2',4,4',5,5'-hexamethoxybiphenyl 
• 43068-14-0 O-methylobtusaquinone 
• 19034-96-9 violastyrene 
• 40268-34-6 Dihydroviolastyrol 
• 148460-80-4 (S)-5-Bromo-N-<(1-ethyl-2-pyrrolidinyl)methyl>-3-hydroxy-6-methoxysalicylamide 
• 148460-92-8 (S)-2,3-Bis(benzyloxy)-N-<(1-ethyl-2-pyrrolidinyl)methyl>-6-methoxybenzamide 

Relevant articles and documents

Study on the degradation mechanism and pathway of benzene dye intermediate 4-methoxy-2-nitroaniline: Via multiple methods in Fenton oxidation process

Benzene dye intermediate (BDI) 4-methoxy-2-nitroaniline (4M2NA) wastewater has caused significant environmental concern due to its strong toxicity and potential carcinogenic effects. Reports concerning the degradation of 4M2NA by advanced oxidation process are limited. In this study, 4M2NA degradation by Fenton oxidation has been studied to obtain more insights into the reaction mechanism involved in the oxidation of 4M2NA. Results showed that when the 4M2NA (100 mg L-1) was completely decomposed, the TOC removal efficiency was only 30.70-31.54%, suggesting that some by-products highly recalcitrant to the Fenton oxidation were produced. UV-Vis spectra analysis based on Gauss peak fitting, HPLC analysis combined with two-dimensional correlation spectroscopy and GC-MS detection were carried out to clarify the degradation mechanism and pathway of 4M2NA. A total of nineteen reaction intermediates were identified and two possible degradation pathways were illustrated. Theoretical TOC calculated based on the concentration of oxalic acid, acetic acid, formic acid, and 4M2NA in the degradation process was nearly 94.41-97.11% of the measured TOC, indicating that the oxalic acid, acetic acid and formic acid were the main products. Finally, the predominant degradation pathway was proposed. These results could provide significant information to better understand the degradation mechanism of 4M2NA.

A Catalyst-Controlled Aerobic Coupling of ortho-Quinones and Phenols Applied to the Synthesis of Aryl Ethers

ortho-Quinones are underutilized six-carbon-atom building blocks. We herein describe an approach for controlling their reactivity with copper that gives rise to a catalytic aerobic cross-coupling with phenols. The resulting aryl ethers are generated in high yield across a broad substrate scope under mild conditions. This method represents a unique example where the covalent modification of an ortho-quinone is catalyzed by a transition metal, creating new opportunities for their utilization in synthesis.

H2O2 in WEB: a highly efficient catalyst system for the Dakin reaction

Without using any transition metal catalyst, ligand, base, toxic or hazardous reagent, additives/promoters and organic solvent, green Dakin reactions have been successfully carried out by using H2O2 in a natural feedstock extract. The reaction proceeds in neat 'Water Extract of Banana' (WEB) at room temperature under aerobic conditions in very short reaction times and, therefore, it is an evergreen and environmentally sound alternative to the existing protocols for the Dakin reaction. In our system, the reaction was found to afford excellent yield for the desired product with different electron-withdrawing and electron-donating hydroxylated benzaldehydes.