828261-34-3Relevant articles and documents
Conformational studies of 4-N-carbamoyldeoxycytidine derivatives and synthesis and hybridization properties of oligodeoxyribonucleotides incorporating these modified bases
Miyata, Kenichi,Kobori, Akio,Tamamushi, Ryuji,Ohkubo, Akihiro,Taguchi, Haruhiko,Seio, Kohji,Sekine, Mitsuo
, p. 3626 - 3637 (2006)
Deoxycytidine derivatives modified with various N-substituted carbamoyl groups at the 4-amino group were synthesized. The detailed 1H NMR studies suggest that the 3′,5′-O-disilylated N- carbamoyldeoxycytidine derivative 11 exists as a species h
Synthesis and hybridization affinity of oligodeoxyribonucleotides incorporating 4-N-(N-arylcarbamoyl)deoxycytidine derivatives
Miyata, Kenichi,Tamamushi, Ryuji,Ohkubo, Akihiro,Taguchi, Haruhiko,Seio, Kohji,Sekine, Mitsuo
, p. 9365 - 9368 (2007/10/03)
Modified oligodeoxynucleotides incorporating 4-N-(N-arylcarbamoyl)-dC derivatives 1a-c were synthesized. The 1H NMR spectra of 1a-c suggest that the carbamoyl group forms an intramolecular hydrogen bond with the cytosine ring nitrogen atom so t