82827-55-2

Upstream product

• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 32503-27-8 tetra(n-butyl)ammonium hydrogensulfate 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 118-93-4 o-hydroxyacetophenone 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 1228934-37-9 1-{2-[3-{4-(2-chlorobenzoyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-36-8 1-{2-[3-{4-(4-chlorobenzoyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-32-4 1-{2-[3-{4-(4-chlorobenzyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-33-5 1-{2-[3-{4-(2-chlorobenzyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 117023-41-3 1-[2-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-ethanone 

Relevant academic research and scientific papers

Synthesis, evaluation and computational studies on a series of acetophenone based 1-(aryloxypropyl)-4-(chloroaryl) piperazines as potential atypical antipsychotics

A series of 1-(aryloxypropyl)-4-(chloroaryl) piperazines have been synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced mesh climbing and stereotypy assays in mice. The compounds 11 and 12 have emerged

Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-piperidines and Structurally Related Compounds

A series of 4-(diarylhydroxymethyl)-1-piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1--1-piperidinyl>propoxy>-3-methoxyphenyl>ethanone (1, AHR-5333) was more potent than oxatomide and terfenadine in this assay.

4-phenylpropyl-indoles having antiarythmic activity

Novel 4-phenylpropyl-indoles of the formula STR1 wherein R and R1 are individually selected from the group consisting of hydrogen, linear alkyl of 1 to 5 carbon atoms, branched alkyl of 3 to 5 carbon atoms, cycloalkyl of 3 to 7 carbon atoms cyc