82827-55-2

Upstream product

• 118-93-4 o-hydroxyacetophenone 
• 109-70-6 1.3-chlorobromopropane 
• 632-02-0 3-chloropropyl p-toluenesulfonate 
• 32503-27-8 tetra(n-butyl)ammonium hydrogensulfate 
• 582-24-1 1-phenyl-2-hydroxyethanone 

Downstream Products

• 117023-41-3 1-[2-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-ethanone 
• 1228934-33-5 1-{2-[3-{4-(2-chlorobenzyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-32-4 1-{2-[3-{4-(4-chlorobenzyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-36-8 1-{2-[3-{4-(4-chlorobenzoyl)piperazin-1-yl}propoxy]phenyl}ethanone 
• 1228934-37-9 1-{2-[3-{4-(2-chlorobenzoyl)piperazin-1-yl}propoxy]phenyl}ethanone 

Relevant academic research and scientific papers

Synthesis, evaluation and computational studies on a series of acetophenone based 1-(aryloxypropyl)-4-(chloroaryl) piperazines as potential atypical antipsychotics

A series of 1-(aryloxypropyl)-4-(chloroaryl) piperazines have been synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced mesh climbing and stereotypy assays in mice. The compounds 11 and 12 have emerged

4-phenylpropyl-indoles having antiarythmic activity

Novel 4-phenylpropyl-indoles of the formula STR1 wherein R and R1 are individually selected from the group consisting of hydrogen, linear alkyl of 1 to 5 carbon atoms, branched alkyl of 3 to 5 carbon atoms, cycloalkyl of 3 to 7 carbon atoms cyc

Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-piperidines and Structurally Related Compounds

A series of 4-(diarylhydroxymethyl)-1-piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1--1-piperidinyl>propoxy>-3-methoxyphenyl>ethanone (1, AHR-5333) was more potent than oxatomide and terfenadine in this assay.