82845-20-3 Usage
Uses
Used in Pharmaceutical Synthesis:
(DIETHOXYPHOSPHORYL)DIFLUOROMETHYLZINC BROMIDE is used as a reagent for the synthesis of pharmaceutical compounds. Its ability to facilitate various chemical reactions, including cross-coupling and C-H functionalization, makes it a crucial component in the development of new drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, (DIETHOXYPHOSPHORYL)DIFLUOROMETHYLZINC BROMIDE is used as a reagent for the synthesis of agrochemicals. Its high reactivity and selectivity contribute to the creation of effective and targeted agrochemical products.
Used in Organic Chemistry Research:
(DIETHOXYPHOSPHORYL)DIFLUOROMETHYLZINC BROMIDE is used as a research tool in the field of organic chemistry. Its unique properties and reactivity make it an indispensable compound for exploring new reaction pathways and developing innovative synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 82845-20-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,8,4 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 82845-20:
(7*8)+(6*2)+(5*8)+(4*4)+(3*5)+(2*2)+(1*0)=143
143 % 10 = 3
So 82845-20-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H10F2O3P.BrH.Zn/c1-3-9-11(8,5(6)7)10-4-2;;/h3-4H2,1-2H3;1H;/q;;+1/p-1/rC5H10BrF2O3PZn/c1-3-10-12(9,11-4-2)5(7,8)13-6/h3-4H2,1-2H3
82845-20-3Relevant articles and documents
TYROSINE PHOSPHATASE SCAFOLD SYNTHESIS
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Page 3, (2010/02/09)
Disclosed are 4-(difluoromethylene)phosphonate cinnamic acid derivatives as a molecular scaffold for the preparation of protein tyrosine phosphatase inhibitors. The invention also relates to a process for the combinatorial preparation of protein tyrosine phospatase inhibitors possessing a 4-(difluoromethylene)phosphonate cinnamic acid/ester molecular scaffold
Preparation and synthetic application of diethyl 2-oxo-1,1-difluorophosphonates
Tsai, Hou-Jen
, p. 247 - 259 (2007/10/03)
Reaction of diethyl(bromodifluoromethyl)phosphonate (EtO)2P(O)CF2Br 1 with activated zinc gave [(diethoxyphosphonyl)difluoromethyl]zinc bromide (EtO)2P(O)CF2ZnBr 2, which was acylated with various acylating agents to afford diethyl 2-oxo-1,1-difluorophosphonates (EtO)2P(O)CF2C(O)R 4 in good yields. Treatment of phosphonates 4 such as diethyl 2-oxo-1,1-difluoropropylphosphonate (EtO)2P(O)CF2C(O)CH3 4a, ethyl difluoro(diethoxyphosphonyl)pyruvate (EtO)2P(O)CF2C(O)CO2Et 4e and N,N-diethyldifluoro(diethoxyphosphonyl)acetamide (EtO)2P(O)CF2C(O)NEt2 4h with Grignard reagents R'MgX provided 1,1-difluoroolefins R′(CH3)C=CF2, R′(CO2Et)C=CF2 and R′(NEt2) C=CF2, respectively.
